SCHEMBL2256200

SCHEMBL2256200

CC(C)(C)[Si](C)(C)OCCCC[O]

nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DUT P33316 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2256667 0.93 DUT (0.42) DUT
SCHEMBL8063404 0.88 DUT (0.43) DUT
SCHEMBL27241092 0.85 DUT (0.42) DUT
SCHEMBL14245094 0.85 DUT (0.42) DUT
SCHEMBL9007756 0.85 DUT (0.42) DUT
SCHEMBL2255607 0.83 DUT (0.38) DUT
SCHEMBL28538333 0.83 DUT (0.43) DUT
SCHEMBL345800 0.82 DUT (0.38) DUT
SCHEMBL3272074 0.80 DUT (0.37) DUT
SCHEMBL5856290 0.80 DUT (0.37) DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9073885-B2 Vitamin D3 lactone derivatives TEIJIN PHARMA LIMITED (JP) 2015-07-07 US disclosed
EP-1589009-B1 VITAMIN D3 LACTONE DERIVATIVE TEIJIN PHARMA LTD (JP) 2014-10-08 EP disclosed
EP-2363390-A1 DERIVED LACTAM FROM D3 VITAMIN Teijin Pharma Limited (JP) 2011-09-07 EP disclosed
US-20110207944-A1 VITAMIN D3 LACTAM DERIVATIVE TEIJIN PHARMA LIMITED (JP) 2011-08-25 US disclosed
US-20060148768-A1 Vitamin d3 lactone derivatives TEIJIN LIMITED (JP) 2006-07-06 US disclosed
EP-1589009-A1 VITAMIN D3 LACTONE DERIVATIVE Teijin Pharma Limited (JP) 2005-10-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060148768-A1 Vitamin d3 lactone derivatives VDR, CYP24A1, CYP2R1 DUT 2761/4885
US-20110207944-A1 VITAMIN D3 LACTAM DERIVATIVE VDR, CYP24A1, CYP2R1 DUT 3635/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.