SCHEMBL22562269

SCHEMBL22562269

CCC1=CC(c2ccccc2N)=CC(C)C1

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
HSD17B10 Q99714 1/20 0.32
NOS3 P29474 1/20 0.31
NOS2 P35228 1/20 0.31
MEN1 O00255 1/20 0.31
USP2 O75604 1/20 0.31
GAA P10253 1/20 0.31
KMT2A Q03164 1/20 0.31
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22782331 0.71 NOS3 (0.34) NOS3NOS2
SCHEMBL20629280 0.68 ALDH1A1 (0.40) ALDH1A1L3MBTL1HSD17B10NOS3NOS2
SCHEMBL22562268 0.64 ALDH1A1 (0.39) ALDH1A1L3MBTL1HSD17B10NOS3NOS2
SCHEMBL20860413 0.61 ALDH1A1 (0.40) ALDH1A1L3MBTL1HSD17B10NOS3NOS2
SCHEMBL22780700 0.61 ALDH1A1 (0.40) ALDH1A1L3MBTL1HSD17B10NOS3NOS2
SCHEMBL8786714 0.60 ALDH1A1 (0.43) ALDH1A1L3MBTL1HSD17B10NOS3NOS2
SCHEMBL11550868 0.59 ALDH1A1 (0.59) ALDH1A1L3MBTL1HSD17B10MEN1KMT2A
SCHEMBL8157632 0.59 NOS3 (0.50) NOS3NOS2
SCHEMBL27471913 0.58 ALDH1A1 (0.56) ALDH1A1L3MBTL1HSD17B10MEN1KMT2A
SCHEMBL169281 0.58 ALDH1A1 (1.00) ALDH1A1L3MBTL1HSD17B10MEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3725793-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND Samsung Electronics Co., Ltd. (KR) 2020-10-21 EP disclosed