Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 7/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22562431 | 0.95 | GABRG2 (0.35) | GABRG2GABRB3GABRA5GABRA3TRPA1 | |
| SCHEMBL22562267 | 0.92 | ALDH1A3 (0.34) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| SCHEMBL22562451 | 0.91 | GABRG2 (0.40) | GABRG2GABRB3GABRA5GABRA3TRPA1 | |
| SCHEMBL22562272 | 0.89 | ALDH1A3 (0.36) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| SCHEMBL22562396 | 0.89 | GABRG2 (0.38) | GABRG2GABRB3GABRA5GABRA3TRPA1 | |
| SCHEMBL22562448 | 0.88 | ALDH1A3 (0.45) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| SCHEMBL22562258 | 0.88 | ALDH1A3 (0.40) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| SCHEMBL22562282 | 0.87 | PTGER4 (0.35) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| SCHEMBL19919474 | 0.85 | GABRG2 (0.41) | GABRG2GABRB3GABRA5GABRA3TRPA1 | |
| SCHEMBL21546720 | 0.85 | ADRA2C (0.37) | GABRG2GABRB3GABRA5GABRA3TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3418278-B1 | ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2020-10-21 | — | — | EP | disclosed |