Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19502964 | 0.83 | KMT2A (0.46) | BMP1L3MBTL1CYP2D6KMT2A | |
| SCHEMBL19502961 | 0.83 | KMT2A (0.46) | BMP1L3MBTL1CYP2D6KMT2A | |
| SCHEMBL19502956 | 0.65 | BMP1 (0.40) | BMP1 | |
| SCHEMBL1508734 | 0.64 | CYP2D6 (0.42) | L3MBTL1CYP2D6KMT2A | |
| SCHEMBL235261 | 0.63 | CYP2D6 (0.45) | L3MBTL1CYP2D6KMT2A | |
| SCHEMBL19193984 | 0.63 | L3MBTL1 (0.54) | L3MBTL1CYP2D6KMT2A | |
| SCHEMBL27570822 | 0.63 | L3MBTL1 (0.54) | L3MBTL1CYP2D6KMT2A | |
| SCHEMBL27551142 | 0.63 | L3MBTL1 (0.54) | L3MBTL1CYP2D6KMT2A | |
| SCHEMBL8249385 | 0.62 | LMNA (0.50) | L3MBTL1CYP2D6KMT2A | |
| SCHEMBL24269352 | 0.62 | CYP2D6 (0.44) | L3MBTL1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3464273-B9 | IMIDAZOLONE COMPOUNDS AS HUMAN NEUTROPHIL ELASTASE INHIBITORS | CHIESI FARM SPA (IT) | 2020-10-21 | — | — | EP | disclosed |