Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ITGB2 | P05107 | 5/20 | 0.44 |
| ▸ | ICAM1 | P05362 | 5/20 | 0.44 |
| ▸ | ITGAL | P20701 | 5/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19146542 | 0.85 | KMT2A (0.58) | KMT2ATSHRITGB2ICAM1ITGAL | |
| SCHEMBL19146023 | 0.83 | KMT2A (0.57) | KMT2ATSHRITGB2ICAM1ITGAL | |
| SCHEMBL19146563 | 0.80 | KMT2A (0.52) | KMT2ATSHRITGB2ICAM1ITGAL | |
| SCHEMBL8618112 | 0.79 | KMT2A (0.61) | KMT2ATSHRNAMPTRAB9ANPC1 | |
| SCHEMBL19146009 | 0.78 | KMT2A (0.58) | KMT2ATSHRITGB2ICAM1ITGAL | |
| SCHEMBL19146399 | 0.78 | KMT2A (0.51) | KMT2ATSHRITGB2ICAM1ITGAL | |
| SCHEMBL28877334 | 0.78 | TSHR (0.62) | KMT2ATSHRITGB2ICAM1ITGAL | |
| SCHEMBL22348983 | 0.77 | KMT2A (0.56) | KMT2ATSHRITGB2ICAM1ITGAL | |
| SCHEMBL19146650 | 0.76 | KMT2A (0.52) | KMT2ATSHRITGB2ICAM1ITGAL | |
| SCHEMBL26972367 | 0.76 | KMT2A (0.52) | KMT2ATSHRITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3377546-B1 | PROCESS FOR THE PREPARATION OF HYDROXYETHYLPYRROLIDONE METHACRYLATE/GLYCIDYL METHACRYLATE COPOLYMERS | ISP INVESTMENTS LLC (US) | 2020-10-21 | — | — | EP | disclosed |