SCHEMBL8618112

SCHEMBL8618112

C=CC(=O)NCCN1CCCC1=O

nearest known ligand 0.61

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.61
TSHR P16473 3/20 0.55
NAMPT P43490 1/20 0.44
RAB9A P51151 3/20 0.43
NPC1 O15118 2/20 0.43
MEN1 O00255 1/20 0.43
ALDH1A1 P00352 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19145898 0.94 KMT2A (0.55) KMT2ATSHRNAMPTRAB9ANPC1
SCHEMBL24649557 0.91 KMT2A (0.53) KMT2ATSHRRAB9ANPC1MEN1
SCHEMBL19146028 0.88 KMT2A (0.49) KMT2ATSHRRAB9ANPC1MEN1
SCHEMBL1094092 0.87 KMT2A (0.48) KMT2ATSHRRAB9ANPC1MEN1
SCHEMBL24649595 0.85 RAB9A (0.50) KMT2ATSHRRAB9ANPC1MEN1
SCHEMBL7626828 0.84 TSHR (0.46) KMT2ATSHRRAB9ANPC1MEN1
SCHEMBL19146013 0.83 RAB9A (0.46) KMT2ATSHRRAB9ANPC1MEN1
SCHEMBL10809608 0.83 KMT2A (0.44) KMT2ATSHRRAB9ANPC1MEN1
SCHEMBL10812760 0.83 SMN1; SMN2 (0.45) KMT2ATSHRRAB9ANPC1MEN1
SCHEMBL19146542 0.82 KMT2A (0.58) KMT2ATSHRNAMPTRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992013014-A1 HAIR FIXATIVE POLYMERS ISP INVESTMENTS INC. (US) 1992-08-06 WO claimed
US-11912831-B2 Hydroxyethylpyrrolidone ethacrylate/glycidyl ethacrylate copolymers ISP INVESTMENTS LLC (US) 2024-02-27 US disclosed
US-11912831-B2 Hydroxyethylpyrrolidone ethacrylate/glycidyl ethacrylate copolymers ISP INVESTMENTS LLC (US) 2024-02-27 US disclosed
US-11859029-B2 Methods of synthesis of homopolymers and non-homopolymers comprising repeating units derived from monomers comprising lactam and acryloyl moieties in an aqueous medium ISP INVESTMENTS LLC (US) 2024-01-02 US disclosed
US-11859029-B2 Methods of synthesis of homopolymers and non-homopolymers comprising repeating units derived from monomers comprising lactam and acryloyl moieties in an aqueous medium ISP INVESTMENTS LLC (US) 2024-01-02 US disclosed
US-11001751-B2 Crosslinked polymers derived from monomers having acryloyl and lactam moieties and sulfonic acid/sulfonate comonomers, compositions thereof, and applications thereof HERCULES LLC (US) 2021-05-11 US disclosed
US-10905636-B2 Block copolymers comprising repeating units derived from monomers comprising lactam and acryloyl moieties and hydrophobic monomers, compositions, and applications thereof ISP INVESTMENTS LLC (US) 2021-02-02 US disclosed
US-20200407470-A1 METHODS OF SYNTHESIS OF HOMOPOLYMERS AND NON-HOMOPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES IN AN AQUEOUS MEDIUM ISP INVESTMENTS LLC (US) 2020-12-31 US disclosed
US-10876015-B2 Coating compositions for forming toner coatings ISP INVESTMENTS LLC (US) 2020-12-29 US disclosed
US-10865264-B2 Hydroxyethylpyrrolidone methacrylate/glycidyl methacrylate copolymers ISP INVESTMENTS LLC (US) 2020-12-15 US disclosed
US-20190151224-A1 PERSONAL CARE COMPOSITIONS COMPRISING COPOLYMERS OF CATIONIC MONOMERS AND ACRYLOYL LACTAM BASED MONOMERS, PROCESS FOR THE SAME AND METHOD OF USE ISP INVESTMENTS LLC (US) 2019-05-23 US disclosed
US-20190015304-A1 BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES AND HYDROPHOBIC MONOMERS, COMPOSITIONS, AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2019-01-17 US disclosed
WO-2018132370-A1 HIGH MOLECULAR WEIGHT BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES AND HYDROPHILIC MONOMERS, COMPOSITIONS, AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2018-07-19 WO disclosed
WO-2018132548-A1 CROSS-LINKED BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES, COMPOSITIONS, AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2018-07-19 WO disclosed
WO-2018017570-A1 A HAIR STRAIGHTENING AND STYLING COMPOSITION, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF ISP INVESTMENTS LLC (US) 2018-01-25 WO disclosed
WO-2017123572-A1 BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES AND HYDROPHOBIC MONOMERS, COMPOSITIONS, AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2017-07-20 WO disclosed
EP-0320821-B1 Silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1998-05-13 EP disclosed
WO-1992013014-A1 HAIR FIXATIVE POLYMERS ISP INVESTMENTS INC. (US) 1992-08-06 WO disclosed
US-5037930-A Heterocyclic quaternized nitrogen-containing cellulosic graft polymers GAF CHEMICALS CORPORATION (US) 1991-08-06 US disclosed
US-4293641-A NITROGEN CONTAINING ADDITION POLYMER AND HYDROQUINONE USED FOR COLOR SEPARATION FUJI PHOTO FILM CO., LTD. (JP) 1981-10-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11912831-B2 Hydroxyethylpyrrolidone ethacrylate/glycidyl ethacrylate copolymers MMAB, PCNA, HMBS KMT2A 1105/4885TSHR 4725/4885NAMPT 3809/4885
US-20190015304-A1 BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES AND HYDROPHOBIC MONOMERS, COMPOSITIONS, AND APPLICATIONS THEREOF F9, ADCY9, MMS19 KMT2A 4458/4885TSHR 1628/4885NAMPT 4407/4885
US-10905636-B2 Block copolymers comprising repeating units derived from monomers comprising lactam and acryloyl moieties and hydrophobic monomers, compositions, and applications thereof F9, ADCY9, MMS19 KMT2A 4458/4885TSHR 1628/4885NAMPT 4407/4885
US-11001751-B2 Crosslinked polymers derived from monomers having acryloyl and lactam moieties and sulfonic acid/sulfonate comonomers, compositions thereof, and applications thereof CAD, STS, COASY KMT2A 3224/4885TSHR 4795/4885NAMPT 2118/4885
US-20190151224-A1 PERSONAL CARE COMPOSITIONS COMPRISING COPOLYMERS OF CATIONIC MONOMERS AND ACRYLOYL LACTAM BASED MONOMERS, PROCESS FOR THE SAME AND METHOD OF USE AADAC, KRT18, AAAS KMT2A 807/4885TSHR 3082/4885NAMPT 3425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.