SCHEMBL22563335

SCHEMBL22563335

NC(=O)[C@H](O)C[C@@H](O)C(O)C(O)CO

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
USP2 O75604 1/20 0.43
SLCO1B1 Q9Y6L6 1/20 0.43
TDP1 Q9NUW8 1/20 0.42
PDE4A P27815 1/20 0.41
OR51E2 Q9H255 1/20 0.33
KDM4E B2RXH2 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28305765 0.86 USP2 (0.37) LMNAL3MBTL1USP2SLCO1B1TDP1
Xylitol SCHEMBL4750185 0.80 LMNA (0.59) LMNAL3MBTL1USP2SLCO1B1TDP1
SCHEMBL2256434 0.79 PDE4A (0.54) LMNAL3MBTL1USP2SLCO1B1TDP1
Adonitol SCHEMBL28862972 0.75 LMNA (0.53) LMNAL3MBTL1USP2SLCO1B1TDP1
Mannitol SCHEMBL1504919 0.75 LMNA (0.69) LMNAL3MBTL1USP2SLCO1B1TDP1
Mannitol SCHEMBL28204430 0.75 LMNA (0.69) LMNAL3MBTL1USP2SLCO1B1TDP1
SCHEMBL5703642 0.74 PDE4A (0.60) LMNAL3MBTL1USP2SLCO1B1TDP1
SCHEMBL122819 0.73 PDE4A (0.52) LMNAL3MBTL1USP2SLCO1B1TDP1
SCHEMBL6665411 0.73 PDE4A (0.52) LMNAL3MBTL1USP2SLCO1B1TDP1
SCHEMBL18902607 0.73 PGD (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3322767-B1 METHODS AND UTILISATIONS USING STABILIZED NANOPARTICLE COMPOSITIONS COMPRISING IONS SAUDI ARABIAN OIL CO (SA) 2020-10-21 EP disclosed