Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGD | P52209 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18902613 | 1.00 | PGD (0.43) | PGD | |
| SCHEMBL18902559 | 0.78 | PGD (0.36) | PGD | |
| SCHEMBL8722958 | 0.77 | SLC7A5 (0.31) | — | |
| SCHEMBL5035757 | 0.75 | PGD (0.45) | PGD | |
| SCHEMBL8587984 | 0.75 | — | — | |
| SCHEMBL22563335 | 0.73 | LMNA (0.43) | — | |
| SCHEMBL3159244 | 0.72 | — | — | |
| SCHEMBL3505756 | 0.72 | — | — | |
| SCHEMBL3168971 | 0.72 | — | — | |
| SCHEMBL3159259 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3173408-A1 | PHENYL TETRAHYDROISOQUINOLINE COMPOUND SUBSTITUTED WITH HETEROARYL | Taisho Pharmaceutical Co., Ltd. (JP) | 2017-05-31 | — | — | EP | disclosed |