Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL249412 | 0.83 | ALDH1A1 (0.43) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| SCHEMBL2333542 | 0.83 | ALDH1A1 (0.43) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| SCHEMBL2318595 | 0.78 | CYP1A2 (0.32) | CYP1A2 | |
| SCHEMBL7295227 | 0.77 | MEN1 (0.39) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| SCHEMBL2411016 | 0.76 | CYP1A2 (0.32) | CYP1A2 | |
| SCHEMBL386156 | 0.76 | CYP1A2 (0.55) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| SCHEMBL2252554 | 0.76 | ALDH1A1 (0.42) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| SCHEMBL2251412 | 0.76 | ALDH1A1 (0.42) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| SCHEMBL4166774 | 0.74 | NOS1 (0.32) | — | |
| SCHEMBL386939 | 0.74 | HSD17B10 (0.44) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1434763-B1 | BETA-LACTAMYL VASOPRESSIN V1A ANTAGONISTS | AZEVAN PHARMACEUTICALS INC (US) | 2018-01-17 | — | — | EP | disclosed |
| CN-104826290-B | The golf of layer composition is covered with photostability and durability | 阿库施耐特公司 | 2017-06-23 | — | — | CN | disclosed |
| CN-105833483-A | Multi-piece golf ball comprising low hardness gradient core | 阿库施耐特公司 | 2016-08-10 | — | — | CN | disclosed |
| CN-102526990-B | Comprise the double-core golf of zero gradient center and positive gradient outer nuclear layer | 阿库施耐特公司 | 2016-08-03 | — | — | CN | disclosed |
| CN-102526994-B | Multi-piece golf balls including low hardness gradient cores | 阿库施耐特公司 | 2016-06-08 | — | — | CN | disclosed |
| US-9006225-B2 | Stable pharmaceutical composition | ASAHI KASEI PHARMA CORPORATION (JP) | 2015-04-14 | — | — | US | disclosed |
| EP-1916244-B1 | THIOPHENE COMPOUND HAVING SULFONYL GROUP AND PROCESS FOR PRODUCING THE SAME | NISSAN CHEMICAL IND LTD (JP) | 2013-12-04 | — | — | EP | disclosed |
| CN-101282959-B | Thiophene compound having sulfonyl group and method for producing same | NISSAN CHEMICAL IND LTD | 2013-04-17 | — | — | CN | disclosed |
| EP-1882694-B1 | OLIGOMERS AND POLYMERS OF THIOPHENE COMPOUNDS HAVING PHOSPHORIC ESTER AND PROCESS FOR PRODUCING THE SAME | NISSAN CHEMICAL IND LTD (JP) | 2013-04-03 | — | — | EP | disclosed |
| US-8030438-B2 | Thiophene compound having phosphoric ester and process for producing the same | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-10-04 | — | — | US | disclosed |
| EP-0653066-A1 | PHOTOACTIVATABLE CHEMILUMINESCENT MATRICES | BEHRINGWERKE Aktiengesellschaft (DE) | 1995-05-17 | — | — | EP | disclosed |
| US-5391556-A | Thrombin inhibitors | KARL THOMAE GMBH (DE) | 1995-02-21 | — | — | US | disclosed |
| US-5340716-A | Assay method utilizing photoactivated chemiluminescent label | SNYTEX (U.S.A.) INC. (US) | 1994-08-23 | — | — | US | disclosed |
| WO-1994003812-A1 | PHOTOACTIVATABLE CHEMILUMINESCENT MATRICES | SYNTEX (U.S.A.) INC. (US) | 1994-02-17 | — | — | WO | disclosed |
| EP-0555824-A1 | N-alpha-arylsulfonylated benzimidazolylalaninamide derivatives, medicaments based thereon and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-08-18 | — | — | EP | disclosed |
| EP-0515194-A2 | Assay methods utilizing induced luminescence | BEHRINGWERKE Aktiengesellschaft (DE) | 1992-11-25 | — | — | EP | disclosed |
| US-4818814-A | COLORFASTNESS | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-04-04 | — | — | US | disclosed |
| EP-0027906-B1 | PROCESS FOR PREPARING SULPHON AMIDES | BAYER AG (DE) | 1983-05-25 | — | — | EP | disclosed |
| US-4322214-A | USING A SULFUR OR SULFURIZED VAT DYE IN AN ALKALINE BATH CONTAINING A MERCAPTO COMPOUND AND A SULFITE SALT; LEVELING | ASAHI CHEMICAL COMPANY LIMITED (JP) | 1982-03-30 | — | — | US | disclosed |
| EP-0027906-A1 | Process for preparing sulphon amides | BAYER AG (DE) | 1981-05-06 | — | — | EP | disclosed |