Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.32 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18317227 | 0.85 | CYP1A2 (0.54) | CYP1A2CYP2A6ALDH1A1HPGDHSD17B10 | |
| SCHEMBL67474 | 0.83 | CYP1A2 (0.50) | CYP1A2CYP2A6ALDH1A1HPGDHSD17B10 | |
| SCHEMBL18317416 | 0.78 | ALDH1A1 (0.46) | CYP1A2CYP2A6ALDH1A1HPGDHSD17B10 | |
| SCHEMBL2318595 | 0.78 | CYP1A2 (0.32) | CYP1A2CYP2A6 | |
| SCHEMBL4307895 | 0.77 | CYP1A2 (0.45) | CYP1A2CYP2A6ALDH1A1HPGDHSD17B10 | |
| SCHEMBL2411016 | 0.76 | CYP1A2 (0.32) | CYP1A2CYP2A6 | |
| SCHEMBL2256346 | 0.76 | ALDH1A1 (0.55) | CYP1A2ALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL668081 | 0.76 | CYP1A2 (0.48) | CYP1A2CYP2A6ALDH1A1HPGDHSD17B10 | |
| SCHEMBL9551471 | 0.76 | CYP1A2 (0.48) | CYP1A2CYP2A6ALDH1A1HPGDHSD17B10 | |
| SCHEMBL386939 | 0.74 | HSD17B10 (0.44) | CYP1A2ALDH1A1HPGDHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 681 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11345686-B2 | Aromatic amine derivative, and organic electroluminescent element | IDEMITSU KOSAN CO., LTD. (JP) | 2022-05-31 | — | — | US | claimed |
| EP-3625223-B1 | PYRIMIDINE DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2021-08-11 | — | — | EP | claimed |
| US-20200108068-A1 | PYRIMIDINE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2020-04-09 | — | — | US | claimed |
| EP-3625223-A1 | PYRIMIDINE DERIVATIVES | Idorsia Pharmaceuticals Ltd (CH) | 2020-03-25 | — | — | EP | claimed |
| CN-110621667-A | Pyrimidine derivatives | 爱杜西亚药品有限公司 | 2019-12-27 | — | — | CN | claimed |
| EP-3156403-B1 | AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT | IDEMITSU KOSAN CO (JP) | 2019-08-28 | — | — | EP | claimed |
| US-20190177306-A1 | AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT | IDEMITSU KOSAN CO., LTD. (JP) | 2019-06-13 | — | — | US | claimed |
| WO-2018210992-A1 | PYRIMIDINE DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2018-11-22 | — | — | WO | claimed |
| EP-2778160-B1 | CYCLIC AZINE COMPOUND HAVING NITROGEN-CONTAINING FUSED AROMATIC GROUP, METHOD FOR PRODUCING SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME AS CONSTITUENT COMPONENT | TOSOH CORP (JP) | 2018-01-10 | — | — | EP | claimed |
| US-9391279-B2 | Aromatic amine derivative and organic electroluminescent device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2016-07-12 | — | — | US | claimed |
| CN-101142169-B | Aromatic amine derivative and organic electroluminescent device using the same | IDEMITSU KOSAN CO.,LTD. (JP) | 2011-12-21 | — | — | CN | claimed |
| US-7994316-B2 | 1,3,5-triazine derivative, production method thereof and organic electroluminescence device comprising this as a composing component | TOSOH CORPORATION (JP) | 2011-08-09 | — | — | US | claimed |
| CN-101987822-A | Organic electroluminescent material and application thereof | BEIJING VISIONOX TECHNOLOGY CO | 2011-03-23 | — | — | CN | claimed |
| US-20110034733-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2011-02-10 | — | — | US | claimed |
| US-7737628-B2 | Aromatic amine derivative and organic electroluminescence device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2010-06-15 | — | — | US | claimed |
| US-20090281311-A1 | 1,3,5-TRIAZINE DERIVATIVE, PRODUCTION METHOD THEREOF AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THIS AS A COMPOSING COMPONENT | TOSOH CORPORATION (JP) | 2009-11-12 | — | — | US | claimed |
| EP-1930329-A1 | 1,3,5-TRIAZINE DERIVATIVE, METHOD FOR PRODUCING SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE CONTAINING SAME AS COMPONENT | Tosoh Corporation (JP) | 2008-06-11 | — | — | EP | claimed |
| EP-0866110-B1 | Light-emitting material for organo-electroluminescence device and organic electroluminescence device | TOYO INK MFG CO (JP) | 2004-10-20 | — | — | EP | claimed |
| EP-0934992-B1 | Light-emitting material for organo-electroluminescence device and organic electroluminescence device | TOYO INK MFG CO (JP) | 2004-07-21 | — | — | EP | claimed |
| US-5236941-A | Hypoglycemic agents, diabetes | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-08-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034733-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | TYR, DDC, EML4 | CYP1A2 1093/4885CYP2A6 2958/4885ALDH1A1 272/4885 |
| US-20200108068-A1 | PYRIMIDINE DERIVATIVES | PTGER1, PTGER4, PTGER2 | CYP1A2 115/4885CYP2A6 186/4885ALDH1A1 418/4885 |
| US-20190177306-A1 | AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT | TYR, LEF1, EFNA1 | CYP1A2 156/4885CYP2A6 2548/4885ALDH1A1 263/4885 |
| US-11345686-B2 | Aromatic amine derivative, and organic electroluminescent element | TYR, LEF1, EFNA1 | CYP1A2 156/4885CYP2A6 2548/4885ALDH1A1 263/4885 |
| US-20090281311-A1 | 1,3,5-TRIAZINE DERIVATIVE, PRODUCTION METHOD THEREOF AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THIS AS A COMPOSING COMPONENT | KCNJ2, KCNA4, KCNJ4 | CYP1A2 459/4885CYP2A6 2133/4885ALDH1A1 699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.