SCHEMBL22563771

SCHEMBL22563771

CCc1cccc(N(N)C(=O)NN)c1COc1ccn(-c2ccc(Br)cc2)n1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NR1H4 Q96RI1 1/20 0.33
ALDH1A1 P00352 2/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30
RAB9A P51151 2/20 0.30
SMN1; SMN2 Q16637 2/20 0.30
LMNA P02545 1/20 0.30
NFKB1 P19838 1/20 0.30
NFKB2 Q00653 1/20 0.30
RELA Q04206 1/20 0.30
NPC1 O15118 1/20 0.30
TP53 P04637 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22564023 0.90 ALDH1A1 (0.34) NR1H4ALDH1A1CYP1A2CYP3A4CA12
SCHEMBL19909882 0.90 NR1H4 (0.33) NR1H4ALDH1A1CYP1A2CYP3A4CA12
SCHEMBL22563767 0.88 NR1H4 (0.38) NR1H4ALDH1A1CYP1A2CYP3A4CA12
SCHEMBL22563990 0.85 NR1H4 (0.30) NR1H4
SCHEMBL22564385 0.84 ALDH1A1 (0.35) NR1H4ALDH1A1CYP1A2CYP3A4CA12
SCHEMBL22563920 0.83 ALDH1A1 (0.32) ALDH1A1SMN1; SMN2LMNANPC1TP53
SCHEMBL22563975 0.83 CA12 (0.35) NR1H4ALDH1A1CA12CA1CA2
SCHEMBL22564110 0.83 ALDH1A1 (0.41) NR1H4ALDH1A1CYP1A2CYP3A4CA12
SCHEMBL22563894 0.83 L3MBTL1 (0.35) NR1H4ALDH1A1CYP1A2CYP3A4CA12
SCHEMBL22564091 0.81 NR1H4 (0.38) NR1H4ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2841429-B1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2020-10-21 EP disclosed