Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.32 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.32 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22564283 | 0.90 | NR1H4 (0.38) | IRAK4NR1H4IDO1TDO2SCN9A | |
| SCHEMBL22564143 | 0.89 | IRAK4 (0.47) | IRAK4IDO1TDO2MEN1KMT2A | |
| SCHEMBL22564212 | 0.89 | IRAK4 (0.36) | IRAK4NR1H4IDO1TDO2SCN9A | |
| SCHEMBL22563959 | 0.89 | KCNK3 (0.36) | IRAK4NR1H4IDO1TDO2ALDH1A1 | |
| SCHEMBL22564503 | 0.88 | IRAK4 (0.35) | IRAK4NR1H4IDO1TDO2ALDH1A1 | |
| SCHEMBL22564195 | 0.88 | ALDH1A1 (0.35) | IRAK4IDO1TDO2ALDH1A1ACHE | |
| SCHEMBL18504496 | 0.88 | IRAK4 (0.36) | IRAK4NR1H4IDO1TDO2SCN9A | |
| SCHEMBL22564338 | 0.88 | CTSD (0.35) | NR1H4LMNA | |
| SCHEMBL22564541 | 0.87 | KCNK3 (0.35) | IRAK4IDO1TDO2ALDH1A1ACHE | |
| SCHEMBL22564316 | 0.87 | KCNK3 (0.35) | IRAK4NR1H4IDO1TDO2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |