Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 3/20 | 0.31 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22564043 | 0.93 | NPC1 (0.35) | NPC1KMT2AMAPTNPSR1KDM4E | |
| SCHEMBL18504272 | 0.90 | NPC1 (0.34) | NPC1KMT2AMAPTNPSR1KDM4E | |
| SCHEMBL22564036 | 0.89 | NPC1 (0.34) | NPC1KMT2AMAPTNPSR1KDM4E | |
| SCHEMBL22564198 | 0.89 | ALDH1A1 (0.36) | KMT2AMAPTKDM4EPOLBL3MBTL1 | |
| SCHEMBL22564298 | 0.88 | TSHR (0.39) | MAPTGABRA5JMJD6ALDH1A1LMNA | |
| SCHEMBL22564437 | 0.87 | ALDH1A1 (0.42) | MAPTL3MBTL1JMJD6ALDH1A1LMNA | |
| SCHEMBL22564276 | 0.86 | FOLH1 (0.35) | NR1H4 | |
| SCHEMBL22564537 | 0.85 | PDE5A (0.32) | GABRA5 | |
| SCHEMBL22563906 | 0.85 | LTB4R (0.32) | NR1H4 | |
| SCHEMBL22564290 | 0.85 | MEN1 (0.34) | KMT2AMAPTKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |