Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.31 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.31 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.31 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 2/20 | 0.31 |
| ▸ | MMP9 | P14780 | 2/20 | 0.31 |
| ▸ | MMP13 | P45452 | 2/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.30 |
| ▸ | LIG1 | P18858 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22564310 | 0.92 | PDE5A (0.34) | PDE5ASMPD1MMP1MMP9MMP13 | |
| SCHEMBL22564152 | 0.92 | HCRTR1 (0.31) | HCRTR1HCRTR2LTB4RLTB4R2MAPK8 | |
| SCHEMBL22564142 | 0.91 | ADORA3 (0.31) | HCRTR1HCRTR2LTB4RLTB4R2 | |
| SCHEMBL18505167 | 0.89 | PDE5A (0.33) | PDE5AHCRTR1HCRTR2SMPD1LTB4R | |
| SCHEMBL22564198 | 0.88 | ALDH1A1 (0.36) | HCRTR1HCRTR2MAPK8 | |
| SCHEMBL22564276 | 0.88 | FOLH1 (0.35) | LTB4RLTB4R2 | |
| SCHEMBL22564312 | 0.87 | LTB4R (0.32) | HCRTR1HCRTR2LTB4RLTB4R2 | |
| SCHEMBL22563906 | 0.87 | LTB4R (0.32) | HCRTR1HCRTR2LTB4RLTB4R2 | |
| SCHEMBL22564378 | 0.87 | PDE5A (0.31) | PDE5AHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22564290 | 0.87 | MEN1 (0.34) | HCRTR1HCRTR2LTB4RLTB4R2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |