SCHEMBL22564022

SCHEMBL22564022

Cc1cccc(C(=O)Br)c1COc1ccn(S)n1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC22A12 Q96S37 2/20 0.36
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
SGMS2 Q8NHU3 1/20 0.35
FFAR1 O14842 3/20 0.35
NR1H4 Q96RI1 2/20 0.33
NOTUM Q6P988 1/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
CASP1 P29466 1/20 0.31
HSD17B10 Q99714 1/20 0.31
PKM P14618 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22563910 0.89 KDM4E (0.38) SLC22A12CYP1A2CYP3A4CYP2C9SGMS2
SCHEMBL22563974 0.88 SGMS2 (0.38) SLC22A12CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL22564533 0.88 CD38 (0.37) SLC22A12CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL22564062 0.88 SGMS2 (0.35) SLC22A12CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL22563856 0.87 ALDH1A1 (0.39) SGMS2L3MBTL1LMNAMAPTRAB9A
SCHEMBL22563878 0.87 NR1H4 (0.33) NR1H4PKM
SCHEMBL22564350 0.86 NR1H4 (0.32) NR1H4L3MBTL1
SCHEMBL18504720 0.86 SLC22A12 (0.36) SLC22A12CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL22564179 0.86 HDAC3 (0.40) SLC22A12CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL22564348 0.86 NR1H4 (0.32) NR1H4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2841429-B1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2020-10-21 EP disclosed