Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | JAK1 | P23458 | 2/20 | 0.35 |
| ▸ | JAK3 | P52333 | 2/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22563910 | 0.89 | KDM4E (0.38) | CYP3A4SGMS2FFAR1SLC22A12LMNA | |
| SCHEMBL22564022 | 0.88 | SLC22A12 (0.36) | CYP3A4SGMS2FFAR1SLC22A12LMNA | |
| SCHEMBL22564062 | 0.88 | SGMS2 (0.35) | CYP3A4SGMS2FFAR1SLC22A12CYP1A2 | |
| SCHEMBL22563856 | 0.87 | ALDH1A1 (0.39) | SGMS2LMNAMAPTKMT2ARAB9A | |
| SCHEMBL22564395 | 0.87 | PARP1 (0.36) | CYP3A4PARP1LMNAMAPTKMT2A | |
| SCHEMBL18504397 | 0.86 | CD38 (0.37) | CD38CYP3A4KCNH2JAK2JAK1 | |
| SCHEMBL22564179 | 0.86 | HDAC3 (0.40) | CYP3A4SGMS2FFAR1SLC22A12LMNA | |
| SCHEMBL22564534 | 0.86 | LMNA (0.39) | JAK2JAK1JAK3TYK2PARP1 | |
| SCHEMBL22564134 | 0.85 | PARP1 (0.37) | CD38CYP3A4JAK2JAK1JAK3 | |
| SCHEMBL22564128 | 0.85 | KLKB1 (0.37) | CD38JAK2JAK1JAK3TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |