Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | GUCY1B2 | O75343 | 8/20 | 0.31 |
| ▸ | GUCY1A2 | P33402 | 8/20 | 0.31 |
| ▸ | GUCY1A1 | Q02108 | 8/20 | 0.31 |
| ▸ | GUCY1B1 | Q02153 | 8/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22564059 | 0.90 | TAAR1 (0.35) | PKMHTR1ATAAR1 | |
| SCHEMBL22564096 | 0.87 | HTR1A (0.31) | PKMHTR1ATAAR1 | |
| SCHEMBL22564250 | 0.85 | CYP3A4 (0.37) | PKMHTR1ATAAR1CYP3A4CYP2C9 | |
| SCHEMBL22564067 | 0.84 | ELANE (0.32) | PKMHTR1ATAAR1 | |
| SCHEMBL22563874 | 0.84 | SMN1; SMN2 (0.36) | PKMMAPTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL22564028 | 0.84 | GABRA1 (0.34) | PKMHTR1ATAAR1 | |
| SCHEMBL22563935 | 0.84 | HTR1A (0.31) | PKMHTR1ATAAR1 | |
| SCHEMBL22564332 | 0.84 | MAPT (0.32) | MAPTCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL22564015 | 0.83 | L3MBTL1 (0.33) | MAPTSMN1; SMN2HTR1ATAAR1LMNA | |
| SCHEMBL22564103 | 0.83 | L3MBTL1 (0.39) | MAPTHTR1ATAAR1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |