Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25480233 | 0.87 | HRH3 (0.44) | HRH3KCNH2KDM1A | |
| SCHEMBL23134084 | 0.86 | HRH3 (0.42) | HRH3KCNH2 | |
| SCHEMBL12890856 | 0.85 | HRH3 (0.43) | HRH3KCNH2KDM1A | |
| SCHEMBL27323580 | 0.79 | HRH3 (0.40) | HRH3KCNH2 | |
| SCHEMBL8364993 | 0.79 | HRH3 (0.40) | HRH3KCNH2 | |
| SCHEMBL24501875 | 0.79 | HRH3 (0.40) | HRH3KCNH2 | |
| SCHEMBL24671761 | 0.79 | NCF1 (0.46) | HRH3KCNH2 | |
| SCHEMBL27425159 | 0.76 | HRH3 (0.38) | HRH3KCNH2 | |
| SCHEMBL4034418 | 0.76 | HRH3 (0.41) | HRH3KCNH2 | |
| SCHEMBL27334923 | 0.76 | HRH3 (0.38) | HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020211822-A1 | A CLASS OF BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUNDS FOR TARGETED DEGRADATION OF ANDROGEN RECEPTORS AND USE THEREOF | 成都海创药业有限公司 | 2020-10-22 | — | — | WO | disclosed |