Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 17/20 | 0.61 |
| ▸ | KDR | P35968 | 3/20 | 0.61 |
| ▸ | AXL | P30530 | 4/20 | 0.57 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19711775 | 0.90 | MET (0.62) | METKDRAXLFGFR2 | |
| SCHEMBL23617110 | 0.89 | FGFR2 (0.67) | METKDRAXLFGFR2 | |
| SCHEMBL29822421 | 0.89 | FGFR2 (0.67) | METKDRAXLFGFR2 | |
| SCHEMBL22521278 | 0.88 | MET (0.54) | METKDRAXL | |
| SCHEMBL22521159 | 0.85 | MET (0.63) | METAXLFGFR2 | |
| SCHEMBL13787641 | 0.84 | MET (0.59) | METKDRAXLFGFR2 | |
| SCHEMBL12335707 | 0.84 | MET (0.70) | METKDRAXL | |
| SCHEMBL5223147 | 0.84 | MET (0.58) | METKDRAXLFGFR2 | |
| SCHEMBL13955464 | 0.84 | MET (0.57) | METKDRAXL | |
| SCHEMBL13955466 | 0.84 | MET (0.57) | METKDRAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200331860-A1 | C-Met Modulators and Methods of Use | EXELIXIS INC (US) | 2020-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200331860-A1 | C-Met Modulators and Methods of Use | FLT4, FLT1, MET | MET 3/4885KDR 4/4885AXL 109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.