SCHEMBL2256808

SCHEMBL2256808

Sc1nc2c(S)cccc2s1.[Zn]

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSMD14 O00487 3/20 0.41
COPS5 Q92905 3/20 0.41
ALDH1A1 P00352 8/20 0.38
LMNA P02545 4/20 0.36
SMN1; SMN2 Q16637 4/20 0.36
PDPK1 O15530 1/20 0.36
PDE10A Q9Y233 1/20 0.36
GAA P10253 5/20 0.35
MEN1 O00255 5/20 0.35
KMT2A Q03164 5/20 0.35
KDM4E B2RXH2 4/20 0.35
HPGD P15428 3/20 0.35
RAB9A P51151 3/20 0.35
NPC1 O15118 2/20 0.35
PRNP P04156 1/20 0.35
MAPT P10636 5/20 0.33
TDP1 Q9NUW8 3/20 0.33
MAPK1 P28482 3/20 0.33
PKM P14618 2/20 0.33
PSMB8 P28062 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3067465 0.98 PSMD14 (0.42) PSMD14COPS5ALDH1A1LMNASMN1; SMN2
SCHEMBL2252871 0.96 PSMD14 (0.41) PSMD14COPS5ALDH1A1LMNASMN1; SMN2
SCHEMBL9799782 0.79 PSMD14 (0.41) PSMD14COPS5ALDH1A1LMNASMN1; SMN2
SCHEMBL3790319 0.79 ALDH1A1 (0.58) PSMD14COPS5ALDH1A1LMNASMN1; SMN2
SCHEMBL543766 0.78 ALDH1A1 (0.43) ALDH1A1LMNASMN1; SMN2PDPK1PDE10A
SCHEMBL2750562 0.78 MAPT (0.46) ALDH1A1LMNASMN1; SMN2PDPK1PDE10A
SCHEMBL546270 0.78 ALDH1A1 (0.61) ALDH1A1LMNASMN1; SMN2GAAMEN1
SCHEMBL3622776 0.78 PDPK1 (0.61) ALDH1A1LMNASMN1; SMN2PDPK1PDE10A
SCHEMBL3096248 0.78 LMNA (0.61) ALDH1A1LMNASMN1; SMN2PDE10AGAA
SCHEMBL9260123 0.78 SMN1; SMN2 (0.61) ALDH1A1LMNASMN1; SMN2GAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8273810-B2 Polyisoprene articles and process for making the same ALLEGIANCE CORPORATION (US) 2012-09-25 US claimed
US-20110203596-A1 POLYISOPRENE ARTICLES AND PROCESS FOR MAKING THE SAME ALLEGIANCE CORPORATION (US) 2011-08-25 US claimed
JP-2010536987-A 2010-12-02 JP claimed
EP-2183303-A1 COMPOUNDING FORMULATIONS FOR PRODUCING ARTICLES FROM GUAYULE NATURAL RUBBER Yulex Corporation (US) 2010-05-12 EP claimed
WO-2009025675-A1 COMPOUNDING FORMULATIONS FOR PRODUCING ARTICLES FROM GUAYULE NATURAL RUBBER YULEX CORPORATION (US) 2009-02-26 WO claimed
US-20090054595-A1 Compounding Formulations for Producing Articles from Guayule Natural Rubber YULEX CORPORATION 2009-02-26 US claimed
EP-3574349-B1 FUSIBLE OIL GEL COMPOSITIONS AND METHODS OF MAKING AND USING SAME KRATON POLYMERS US LLC (US) 2025-08-13 EP disclosed
US-11692048-B2 Fusible oil gel compositions and methods of making and using same Kraton Corporation (US) 2023-07-04 US disclosed
CN-110402402-B Fusible oil gel compositions and methods of making and using the same 科腾聚合物美国有限责任公司 2022-01-11 CN disclosed
CN-112280130-A Method for preparing latex film product by using polyisoprene latex 淄博鲁华泓锦新材料股份有限公司 2021-01-29 CN disclosed
US-20200399408-A1 FUSIBLE OIL GEL COMPOSITIONS AND METHODS OF MAKING AND USING SAME KRATON POLYMERS U.S. LLC (US) 2020-12-24 US disclosed
EP-3574349-A1 FUSIBLE OIL GEL COMPOSITIONS AND METHODS OF MAKING AND USING SAME Kraton Polymers U.S. LLC (US) 2019-12-04 EP disclosed
WO-2018165505-A1 FUSIBLE OIL GEL COMPOSITIONS AND METHODS OF MAKING AND USING SAME KRATON POLYMERS U.S. LLC (US) 2018-09-13 WO disclosed
US-20090326102-A1 POLYISOPRENE ARTICLES AND PROCESS FOR MAKING THE SAME ALLEGIANCE CORPORATION 2009-12-31 US disclosed
WO-2009025675-A1 COMPOUNDING FORMULATIONS FOR PRODUCING ARTICLES FROM GUAYULE NATURAL RUBBER YULEX CORPORATION (US) 2009-02-26 WO disclosed
US-20090054595-A1 Compounding Formulations for Producing Articles from Guayule Natural Rubber YULEX CORPORATION 2009-02-26 US disclosed
US-6828387-B2 Surgery gloves ALLEGIANCE CORPORATION 2004-12-07 US disclosed
US-20040169317-A1 Polyisoprene articles and process for making the same ALLEGIANCE CORPORATION 2004-09-02 US disclosed
US-20020173563-A1 Polyisoprene articles and process for making the same ALLEGIANCE CORPORATION 2002-11-21 US disclosed
WO-2002090430-A1 POLYISOPRENE ARTICLES AND PROCESS FOR MAKING THE SAME ALLEGIANCE CORPORATION (US) 2002-11-14 WO disclosed