Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.33 |
| ▸ | CDC25B | P30305 | 6/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.31 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17106843 | 0.83 | HTR1A (0.41) | HSPA5CA1CA2CA9PTPN1 | |
| SCHEMBL17106842 | 0.83 | HTR1A (0.41) | HSPA5CA1CA2CA9PTPN1 | |
| SCHEMBL29397234 | 0.81 | PDE2A (0.43) | HSPA5CA1CA2CA9PTPN1 | |
| SCHEMBL24557909 | 0.81 | PDE2A (0.43) | HSPA5CA1CA2CA9PTPN1 | |
| SCHEMBL22569894 | 0.81 | HRH4 (0.34) | HSPA5PDE2AHRH4HRH3 | |
| SCHEMBL24736805 | 0.76 | PDE4D (0.38) | PDE4DHSPA5CA1CA2CA9 | |
| SCHEMBL29569250 | 0.75 | PDE2A (0.34) | PDE2ABCHEACHETSHRCASP3 | |
| SCHEMBL17131352 | 0.74 | SLC29A1 (0.31) | TSHRCASP3RAB9ASENP8SENP7 | |
| SCHEMBL19343957 | 0.74 | PDE4D (0.34) | PDE4DPDE2AHTR1ABCHEACHE | |
| SCHEMBL19412708 | 0.73 | PTPN1 (0.34) | HSPA5PTPN1CDC25BPDE2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020211672-A1 | CD73 INHIBITORS | BIOARDIS LLC (US) | 2020-10-22 | — | — | WO | disclosed |