Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29127378 | 0.87 | SMN1; SMN2 (0.47) | SMN1; SMN2HTTKMT2AMAPK1POLB | |
| SCHEMBL8539111 | 0.83 | ALDH1A1 (0.42) | SMN1; SMN2KMT2AMAPK1POLBALDH1A1 | |
| SCHEMBL22582787 | 0.81 | KMT2A (0.53) | SMN1; SMN2HTTKMT2AMAPK1POLB | |
| SCHEMBL19451738 | 0.80 | KMT2A (0.46) | SMN1; SMN2HTTKMT2AMAPK1POLB | |
| SCHEMBL23116080 | 0.78 | KMT2A (0.44) | SMN1; SMN2HTTKMT2AMAPK1POLB | |
| SCHEMBL19436510 | 0.78 | KMT2A (0.44) | SMN1; SMN2HTTKMT2AMAPK1POLB | |
| SCHEMBL29031589 | 0.78 | ALDH1A1 (0.46) | SMN1; SMN2HTTKMT2AMAPK1ALDH1A1 | |
| SCHEMBL22599563 | 0.73 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL28432522 | 0.73 | ALDH1A1 (0.57) | SMN1; SMN2HTTKMT2APOLBALDH1A1 | |
| SCHEMBL20944539 | 0.72 | KMT2A (0.44) | SMN1; SMN2HTTKMT2AMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200339515-A1 | PYRAZOLE DERIVATIVE | Sinochem Lantian Co., Ltd. (CN) | 2020-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200339515-A1 | PYRAZOLE DERIVATIVE | SPOUT1, STK39, GPX1 | SMN1; SMN2 2084/4885HTT 3839/4885KMT2A 3381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.