Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25857253 | 0.78 | GAA (0.46) | CYP2C19MEN1KMT2AGAAHTT | |
| SCHEMBL12233464 | 0.75 | POLB (0.53) | POLBCYP1A2CYP2C19LMNACYP2C9 | |
| SCHEMBL23633882 | 0.74 | GAA (0.46) | GAAHTTHDAC3HDAC1HDAC2 | |
| SCHEMBL20716198 | 0.74 | CNR2 (0.39) | HDAC3HDAC1HDAC2 | |
| SCHEMBL25070756 | 0.72 | SPHK2 (0.33) | LMNAGAANPC1RAB9AALDH1A1 | |
| SCHEMBL21790580 | 0.71 | NAAA (0.41) | POLBCYP2D6LMNAHTTSMN1; SMN2 | |
| SCHEMBL23819890 | 0.71 | GAA (0.44) | CYP2C19GAAHTTHDAC3HDAC1 | |
| SCHEMBL22692559 | 0.71 | ESR1 (0.42) | POLBCYP1A2CYP2C19CYP2D6LMNA | |
| SCHEMBL12981588 | 0.71 | CNR2 (0.49) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL22600030 | 0.69 | EPHX1 (0.47) | LMNAMEN1KMT2AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200339596-A1 | FUROXAN-BASED COMPOUNDS AND USES THEREOF | UNIVERSITY OF MASSACHUSETTS | 2020-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200339596-A1 | FUROXAN-BASED COMPOUNDS AND USES THEREOF | PARK7, HTT, PRDX5 | POLB 1874/4885CYP1A2 545/4885CYP2C19 310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.