SCHEMBL25857253

SCHEMBL25857253

CCCCCC(C)(CCCC)Nc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.46
EPHX1 P07099 3/20 0.39
ALDH1A1 P00352 3/20 0.39
HTT P42858 1/20 0.39
KCNH3 Q9ULD8 1/20 0.39
SIGMAR1 Q99720 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
TLR8 Q9NR97 2/20 0.36
TLR7 Q9NYK1 1/20 0.36
ALOX12 P18054 1/20 0.36
CYP2C19 P33261 1/20 0.36
ICMT O60725 1/20 0.36
ALB P02768 1/20 0.36
SOAT2 O75908 1/20 0.36
SOAT1 P35610 1/20 0.36
MEN1 O00255 1/20 0.35
MAPT P10636 1/20 0.35
MAPK1 P28482 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23633882 0.96 GAA (0.46) GAAEPHX1ALDH1A1HTTKCNH3
SCHEMBL23819890 0.93 GAA (0.44) GAAEPHX1ALDH1A1HTTKCNH3
SCHEMBL29038512 0.84 GAA (0.43) GAAALDH1A1NPSR1ALOX12CYP2C19
SCHEMBL1454677 0.83 GAA (0.47) GAAEPHX1ALDH1A1HTTKCNH3
SCHEMBL9146997 0.81 GAA (0.46) GAAEPHX1ALDH1A1HTTKCNH3
SCHEMBL7174301 0.81 GAA (0.46) GAAEPHX1ALDH1A1HTTKCNH3
SCHEMBL1454049 0.81 GAA (0.46) GAAEPHX1ALDH1A1HTTKCNH3
SCHEMBL11329795 0.79 GAA (0.47) GAAEPHX1ALDH1A1HTTKCNH3
SCHEMBL25861368 0.79 GAA (0.40) GAAALDH1A1TLR8
SCHEMBL21790580 0.79 NAAA (0.41) ALDH1A1HTTTLR8TLR7MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11801228-B2 Modified guanidine-containing polymers for biologic delivery THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2023-10-31 US disclosed
US-20230225982-A1 MODIFIED GUANIDINE-CONTAINING POLYMERS FOR BIOLOGIC DELIVERY THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230225982-A1 MODIFIED GUANIDINE-CONTAINING POLYMERS FOR BIOLOGIC DELIVERY GMPS, RNMT, GUCY1A1 GAA 237/4885EPHX1 2873/4885ALDH1A1 1829/4885
US-11801228-B2 Modified guanidine-containing polymers for biologic delivery GMPS, RNMT, GUCY1A1 GAA 237/4885EPHX1 2873/4885ALDH1A1 1829/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.