SCHEMBL22600175

SCHEMBL22600175

C[C@@H](O)CC=C1CCN(C)CC1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23550046 0.76 HRH3 (0.32) HRH3
SCHEMBL6947992 0.74 ESR2 (0.36) HRH3
SCHEMBL12972268 0.72 HRH3 (0.36) HRH3
SCHEMBL6947677 0.70 NOS1 (0.35) HRH3
SCHEMBL24131684 0.70 HRH3 (0.35) HRH3
SCHEMBL17284674 0.70 MAOA (0.37) HRH3
SCHEMBL15322872 0.68 KDM4E (0.33) HRH3
SCHEMBL15082705 0.67 HRH3 (0.36) HRH3
SCHEMBL17282138 0.67 HRH3 (0.33) HRH3
SCHEMBL12374770 0.67 MAOA (0.33) HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3958867-B1 SMALL MOLECULE BROMODOMAIN INHIBITORS AND USES THEREOF CONVERGENE LLC (US) 2024-06-26 EP disclosed
WO-2020219168-A1 SMALL MOLECULE BROMODOMAIN INHIBITORS AND USES THEREOF CONVERGENE, LLC (US) 2020-10-29 WO disclosed