Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CASP2 | P42575 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13032706 | 1.00 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL26178992 | 0.95 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL29300550 | 0.94 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL18623944 | 0.94 | SIGMAR1 (0.54) | ALDH1A1MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL24410021 | 0.94 | MEN1 (0.46) | ALDH1A1MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL5547349 | 0.93 | CASP2 (0.51) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL18118429 | 0.93 | CASP2 (0.51) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL23824100 | 0.93 | CASP2 (0.51) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL254811 | 0.93 | CASP2 (0.51) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL6897984 | 0.93 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2AKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020219753-A1 | HEPARANASE COMPOUNDS AND METHODS OF USE | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2020-10-29 | — | — | WO | disclosed |