Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.51 |
| ▸ | RAB9A | P51151 | 9/20 | 0.51 |
| ▸ | TP53 | P04637 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | GALK1 | P51570 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22601061 | 0.89 | CHRNA7 (0.40) | NPC1RAB9ATP53SMN1; SMN2PKM | |
| SCHEMBL22600839 | 0.88 | RAB9A (0.41) | NPC1RAB9ATP53SMN1; SMN2PKM | |
| SCHEMBL24314307 | 0.88 | RAB9A (0.45) | NPC1RAB9ATP53SMN1; SMN2PKM | |
| SCHEMBL24313789 | 0.88 | NPC1 (0.43) | NPC1RAB9ATP53SMN1; SMN2PKM | |
| SCHEMBL22601146 | 0.86 | NPC1 (0.39) | NPC1RAB9ATP53SMN1; SMN2PKM | |
| SCHEMBL26008098 | 0.86 | SLC16A3 (0.42) | NPC1RAB9ATP53SMN1; SMN2PKM | |
| SCHEMBL24313952 | 0.85 | NPC1 (0.43) | NPC1RAB9ATP53SMN1; SMN2PKM | |
| SCHEMBL24313970 | 0.85 | ALDH1A1 (0.40) | NPC1RAB9ATP53SMN1; SMN2PKM | |
| SCHEMBL24314221 | 0.85 | DRD3 (0.36) | NPC1RAB9ATP53SMN1; SMN2PKM | |
| SCHEMBL24313793 | 0.85 | ALDH1A1 (0.42) | NPC1RAB9ATP53SMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3959202-B1 | ACYL SULFONAMIDES FOR TREATING CANCER | BAYER AG (DE) | 2023-08-16 | — | — | EP | disclosed |
| WO-2020216701-A1 | ACYL SULFONAMIDES FOR TREATING CANCER | BAYER AKTIENGESELLSCHAFT (DE) | 2020-10-29 | — | — | WO | disclosed |