Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.62 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.62 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.62 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.62 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.51 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | THPO | P40225 | 2/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | NPY1R | P25929 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22402681 | 1.00 | PI4KA (0.62) | PI4KAPI4K2BPI4K2API4KBP2RY12 | |
| SCHEMBL1097616 | 1.00 | PI4KA (0.62) | PI4KAPI4K2BPI4K2API4KBP2RY12 | |
| SCHEMBL29444514 | 1.00 | PI4KA (0.62) | PI4KAPI4K2BPI4K2API4KBP2RY12 | |
| SCHEMBL30827092 | 1.00 | PI4KA (0.62) | PI4KAPI4K2BPI4K2API4KBP2RY12 | |
| SCHEMBL16378775 | 1.00 | PI4KA (0.62) | PI4KAPI4K2BPI4K2API4KBP2RY12 | |
| SCHEMBL26361736 | 1.00 | PI4KA (0.62) | PI4KAPI4K2BPI4K2API4KBP2RY12 | |
| SCHEMBL1795484 | 1.00 | PI4KA (0.62) | PI4KAPI4K2BPI4K2API4KBP2RY12 | |
| SCHEMBL21504639 | 0.93 | PI4KA (0.52) | PI4KAPI4K2BPI4K2API4KBP2RY12 | |
| SCHEMBL26937492 | 0.93 | PI4KA (0.52) | PI4KAPI4K2BPI4K2API4KBP2RY12 | |
| SCHEMBL26361740 | 0.93 | PI4KA (0.52) | PI4KAPI4K2BPI4K2API4KBP2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020216327-A1 | DERIVATIVES OF GLYCERO-MANNO-HEPTOSE ADP FOR USE IN MODULATING IMMUNE RESPONSE | SHANGHAI YAO YUAN BIOTECHNOLOGY CO., LTD. (CN) | 2020-10-29 | — | — | WO | disclosed |
| US-20160303110-A1 | METHODS OF TREATING ABNORMAL MUSCULAR ACTIVITY | AUSPEX PHARMACEUTICALS, INC. (US) | 2016-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160303110-A1 | METHODS OF TREATING ABNORMAL MUSCULAR ACTIVITY | PYGM, TNNC1, MUSK | PI4KA 4606/4885PI4K2B 4486/4885PI4K2A 4412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.