SCHEMBL2260153

SCHEMBL2260153

Cc1ccc([I+]c2ccc(CC(C)C)cc2)cc1.Fc1c(F)c(F)c([B-](c2c(F)c(F)c(F)c(F)c2F)(c2c(F)c(F)c(F)c(F)c2F)c2c(F)c(F)c(F)c(F)c2F)c(F)c1F

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.33
PTGS1 P23219 4/20 0.31
PTGS2 P35354 4/20 0.31
LMNA P02545 2/20 0.31
CYP2C9 P11712 2/20 0.31
AKR1C3 P42330 2/20 0.31
CXCR1 P25024 2/20 0.31
CXCR2 P25025 2/20 0.31
ALB P02768 1/20 0.31
ESR1 P03372 1/20 0.31
ALOX5 P09917 1/20 0.31
RARB P10826 1/20 0.31
ADRB3 P13945 1/20 0.31
NFKB1 P19838 1/20 0.31
HTR2A P28223 1/20 0.31
NR1I3 Q14994 1/20 0.31
SLC22A6 Q4U2R8 1/20 0.31
CXCL8 P10145 1/20 0.31
TSHR P16473 1/20 0.31
AKR1C2 P52895 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29408461 0.84 PTGS1 (0.36) EPHX1PTGS1PTGS2LMNACYP2C9
SCHEMBL361556 0.84 PTGS1 (0.40) EPHX1PTGS1PTGS2LMNACYP2C9
Toliodium SCHEMBL1155683 0.84 ACHE (0.37)
Hydrochloric Acid SCHEMBL31093481 0.82 PTGS1 (0.39) EPHX1PTGS1PTGS2LMNACYP2C9
SCHEMBL29408470 0.81 PTGS1 (0.36) EPHX1PTGS1PTGS2LMNACYP2C9
SCHEMBL29351331 0.81 PTGS1 (0.36) EPHX1PTGS1PTGS2LMNACYP2C9
SCHEMBL133838 0.80 SCN5A (0.31)
SCHEMBL1155415 0.78 ACHE (0.34) LMNANFKB1TSHR
SCHEMBL4644260 0.77
SCHEMBL284111 0.77 PTGS1 (0.45) EPHX1PTGS1PTGS2LMNACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070225395-A1 Thermally stable cationic photocurable compositions WOLF JEAN-PIERRE 2007-09-27 US claimed
US-20050165141-A1 Thermally stable cationic photocurable compositions CIBA SPECIALTY CHEMICALS CORP. 2005-07-28 US claimed
EP-2076563-B1 THERMALLY STABLE CATIONIC PHOTOCURABLE COMPOSITIONS BASF SE (DE) 2016-08-17 EP disclosed
US-8084522-B2 Thermally stable cationic photocurable compositions BASF SE (DE) 2011-12-27 US disclosed
US-8003169-B2 Using photoinitiators; discharging plasma ; applying to three-dimensional substrate BASF SE (DE) 2011-08-23 US disclosed
US-20100304284-A1 THERMALLY STABLE CATIONIC PHOTOCURABLE COMPOSITIONS IGM GROUP B.V. (NL) 2010-12-02 US disclosed
EP-1497338-B1 CURING OF COATINGS INDUCED BY PLASMA BASF SE (DE) 2010-09-01 EP disclosed
EP-2076563-A1 THERMALLY STABLE CATIONIC PHOTOCURABLE COMPOSITIONS Ciba Holding Inc. (CH) 2009-07-08 EP disclosed
WO-2008049743-A1 THERMALLY STABLE CATIONIC PHOTOCURABLE COMPOSITIONS CIBA HOLDING INC. (CH) 2008-05-02 WO disclosed
US-20070249484-A1 Process for the Photoactivation and use of a Catalyst by an Inverted Two-Stage Procedure CIBA SPECIALTY CHEMICALS CORP. 2007-10-25 US disclosed
US-20070225395-A1 Thermally stable cationic photocurable compositions WOLF JEAN-PIERRE 2007-09-27 US disclosed
EP-1709099-A2 THERMALLY STABLE CATIONIC PHOTOCURABLE COMPOSITIONS Ciba Specialty Chemicals Holding Inc. (CH) 2006-10-11 EP disclosed
WO-2006008251-A2 PROCESS FOR THE PHOTOACTIVATION AND USE OF A CATALYST BY AN INVERTED TWO-STAGE PROCEDURE CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-01-26 WO disclosed
WO-2005070989-A2 THERMALLY STABLE CATIONIC PHOTOCURABLE COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-08-04 WO disclosed
US-20050165141-A1 Thermally stable cationic photocurable compositions CIBA SPECIALTY CHEMICALS CORP. 2005-07-28 US disclosed
US-20050129859-A1 Curing of coating induced by plasma CIBA CORPORATION 2005-06-16 US disclosed
EP-1497338-A2 CURING OF COATINGS INDUCED BY PLASMA Ciba SC Holding AG (CH) 2005-01-19 EP disclosed
WO-2003089479-A2 CURING OF COATINGS INDUCED BY PLASMA CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-10-30 WO disclosed
US-20010036591-A1 Iodonium salts as latent acid donors IGM GROUP B.V. (NL) 2001-11-01 US disclosed
US-6306555-B1 RADIATION-SENSITIVE COMPOSITION COMPRISING CATIONICALLY OR ACID-CATALYTICALLY POLYMERISABLE OR CROSSLINKABLE COMPOUND OR COMPOUND THAT INCREASES ITS SOLUBILITY IN DEVELOPER UNDER ACTION OF ACID, AND AT LEAST ONE DIARYLIODONIUM SALT CIBA SPECIALTY CHEMICALS CORP. 2001-10-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070249484-A1 Process for the Photoactivation and use of a Catalyst by an Inverted Two-Stage Procedure INF2, CRY2, CCNT2 EPHX1 1872/4885PTGS1 3875/4885PTGS2 1765/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.