SCHEMBL226038

SCHEMBL226038

Cc1nc(N)c2ncn([C@]3(C)O[C@H](CO)[C@@H](O)[C@H]3O)c2n1

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 7/20 0.43
ADORA2B P29275 4/20 0.42
PI4KA P42356 1/20 0.41
PI4K2B Q8TCG2 1/20 0.41
PI4K2A Q9BTU6 1/20 0.41
PI4KB Q9UBF8 1/20 0.41
LMNA P02545 1/20 0.41
NT5E P21589 1/20 0.41
HIF1A Q16665 1/20 0.41
ADORA3 P0DMS8 1/20 0.41
ADORA1 P30542 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20798007 1.00 ADORA2A (0.43) ADORA2AADORA2BPI4KAPI4K2BPI4K2A
Phosphoric Acid SCHEMBL1300003 0.95 RNASEL (0.42) ADORA2AADORA2BPI4KAPI4K2BPI4K2A
SCHEMBL2458493 0.90 ADORA2A (0.41) ADORA2AADORA2BLMNANT5EHIF1A
SCHEMBL6685951 0.90 AHCY (0.46) ADORA2AADORA2BPI4KAPI4K2BPI4K2A
SCHEMBL1938201 0.90 AHCY (0.46) ADORA2AADORA2BPI4KAPI4K2BPI4K2A
SCHEMBL6538264 0.88 ADORA2A (0.57) ADORA2ALMNAADORA3ADORA1
SCHEMBL17460351 0.87 PI4KA (0.35) ADORA2AADORA2BPI4KAPI4K2BPI4K2A
SCHEMBL2458484 0.86 BLM (0.44) LMNAADORA3
SCHEMBL9810700 0.85 ADORA2A (0.41) ADORA2AADORA2BLMNANT5EHIF1A
SCHEMBL3794703 0.84 PI4KA (0.55) ADORA2AADORA2BPI4KAPI4K2BPI4K2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 599 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4384635-A1 IN SITU EPITRANSCRIPTOMIC PROFILING The Broad Institute Inc. (US) 2024-06-19 EP claimed
WO-2024086659-A2 COMPOSITION AND METHODS FOR DETECTING ADENINE MODIFICATIONS THE UNIVERSITY OF CHICAGO (US) 2024-04-25 WO claimed
US-20240011084-A1 METHODS FOR FULL-LENGTH REVERSE TRANSCRIPTION PCR OF LONG RNAs CONTAINING MODIFIED RIBONUCLEOSIDES USING A THERMOSTABLE REVERSE TRANSCRIPTASE NORTHWESTERN UNIVERSITY 2024-01-11 US claimed
CN-115943307-A MR1 ligands and pharmaceutical compositions for immunomodulation 巴塞尔大学 2023-04-07 CN claimed
US-20230099822-A1 MR1 LIGANDS AND PHARMACEUTICAL COMPOSITIONS FOR IMMUNOMODULATION UNIVERSITÄT BASEL (CH) 2023-03-30 US claimed
WO-2023023055-A1 COMPOSITIONS AND METHODS FOR OPTIMIZING TROPISM OF DELIVERY SYSTEMS FOR RNA RENAGADE THERAPEUTICS MANAGEMENT INC. (US) 2023-02-23 WO claimed
WO-2023018756-A1 IN SITU EPITRANSCRIPTOMIC PROFILING THE BROAD INSTITUTE, INC. (US) 2023-02-16 WO claimed
CN-114076805-B Method for enriching methylated adenosine in urine and application thereof 浙江大学 2022-07-26 CN claimed
WO-2022115822-A2 METHODS FOR FULL-LENGTH REVERSE TRANSCRIPTION PCR OF LONG RNAS CONTAINING MODIFIED RIBONUCLEOSIDES USING A THERMOSTABLE REVERSE TRANSCRIPTASE NORTHWESTERN UNIVERSITY (US) 2022-06-02 WO claimed
CN-114076805-A Method for enriching methylated adenosine in urine and application thereof 浙江大学 2022-02-22 CN claimed
WO-2021144475-A1 MR1 LIGANDS AND PHARMACEUTICAL COMPOSITIONS FOR IMMUNOMODULATION UNIVERSITÄT BASEL (CH) 2021-07-22 WO claimed
CN-104804903-B Semiconductor cleaning agent with metal line 恩特格里斯公司 2018-10-30 CN claimed
CN-106399506-A Diagnostic methods for determining prognosis of non-small cell lung cancer 雅培分子公司 2017-02-15 CN claimed
EP-2755986-A1 ENGINEERED NUCLEIC ACIDS AND METHODS OF USE THEREOF Moderna Therapeutics, Inc. (US) 2014-07-23 EP claimed
WO-2013039857-A1 ENGINEERED NUCLEIC ACIDS AND METHODS OF USE THEREOF modeRNA Therapeutics (US) 2013-03-21 WO claimed
WO-2001085220-A1 LABELED NUCLEOSIDES AND METHOD FOR THEIR PREPARATION RNA-TEC N.V. (BE) 2001-11-15 WO claimed
JP-57145898-A None JP disclosed
JP-1083092-A None JP disclosed
EP-0238672-A1 PROCESS FOR DEOXIDIZING ALCOHOL Yamasa Shoyu Kabushiki Kaisha (JP) 1987-09-30 EP disclosed
JP-S57145898-A NOVEL N6, N6-DIMETHYLADENOSINE DERIVATIVE ARAKAWA CHIYOUTAROU KK 1982-09-09 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230099822-A1 MR1 LIGANDS AND PHARMACEUTICAL COMPOSITIONS FOR IMMUNOMODULATION MRGPRX1, MRGPRX2, CD47 ADORA2A 82/4885ADORA2B 133/4885PI4KA 4527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.