Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.50 |
| ▸ | GBA1 | P04062 | 3/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27053889 | 0.92 | TRPA1 (0.48) | TRPA1TRPM8GBA1EPHX1 | |
| SCHEMBL16885318 | 0.86 | TRPA1 (0.43) | TRPA1TRPM8GBA1 | |
| SCHEMBL16885307 | 0.86 | TRPA1 (0.43) | TRPA1TRPM8GBA1 | |
| SCHEMBL16885315 | 0.86 | TRPA1 (0.43) | TRPA1TRPM8GBA1 | |
| SCHEMBL7875684 | 0.86 | TRPA1 (0.43) | TRPA1TRPM8GBA1 | |
| SCHEMBL16885317 | 0.86 | TRPA1 (0.43) | TRPA1TRPM8GBA1 | |
| SCHEMBL16885375 | 0.86 | TRPA1 (0.43) | TRPA1TRPM8GBA1 | |
| SCHEMBL13712036 | 0.82 | — | — | |
| SCHEMBL2307353 | 0.80 | TRPA1 (0.46) | TRPA1TRPM8GBA1EPHX1 | |
| SCHEMBL27053887 | 0.79 | TRPA1 (0.41) | TRPA1TRPM8GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767341-B2 | Lincosamide antibiotics and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-09-26 | — | — | US | disclosed |
| US-11124534-B2 | Lincosamide antibiotics and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-09-21 | — | — | US | disclosed |
| US-20200339620-A1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767341-B2 | Lincosamide antibiotics and uses thereof | LNPEP, LCLAT1, NPEPPS | TRPA1 4665/4885TRPM8 3201/4885GBA1 459/4885 |
| US-11124534-B2 | Lincosamide antibiotics and uses thereof | LNPEP, LCLAT1, NPEPPS | TRPA1 4665/4885TRPM8 3201/4885GBA1 459/4885 |
| US-20200339620-A1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | LNPEP, LCLAT1, NPEPPS | TRPA1 4665/4885TRPM8 3201/4885GBA1 459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.