SCHEMBL8464443

SCHEMBL8464443

C=C(CC)c1cccc(C(=C)C(C)C)c1

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.36
KMT2A Q03164 1/20 0.36
HSD17B10 Q99714 1/20 0.36
SMN1; SMN2 Q16637 3/20 0.32
ATM Q13315 2/20 0.32
LMNA P02545 2/20 0.32
MAPT P10636 2/20 0.32
FURIN P09958 1/20 0.32
XBP1 P17861 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
TAS1R3 Q7RTX0 1/20 0.31
TAS1R1 Q7RTX1 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2260448 0.86 SMN1; SMN2 (0.38) GAAKMT2AHSD17B10SMN1; SMN2ATM
SCHEMBL8464546 0.86 KMT2A (0.39) GAAKMT2AHSD17B10SMN1; SMN2ATM
SCHEMBL8460079 0.80 GRIK2 (0.36) KMT2AHSD17B10SMN1; SMN2LMNAMAPT
SCHEMBL8460946 0.79 FURIN (0.34) KMT2ASMN1; SMN2ATMLMNAMAPT
SCHEMBL18809537 0.76 KMT2A (0.49) GAAKMT2AHSD17B10SMN1; SMN2MAPT
SCHEMBL24675147 0.75 PTGS1 (0.36) HSD17B10SMN1; SMN2ATMLMNAMAPT
SCHEMBL9627367 0.75 CA12 (0.47) GAAHSD17B10SMN1; SMN2LMNAMAPT
SCHEMBL4706020 0.75 C1S (0.48) GAAKMT2AMAPTALDH1A1HPGD
SCHEMBL8444352 0.75 HPGD (0.50) KMT2ASMN1; SMN2MAPTTAS1R3TAS1R1
SCHEMBL8081217 0.75 PARP1 (0.48) KMT2ASMN1; SMN2ATMTAS1R3TAS1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0700963-B1 Polymeric N-aryl substituted and N-alkaryl substituted diphenyldiamines GOODYEAR TIRE & RUBBER (US) 1999-04-14 EP claimed
US-5726248-A ANTIOXIDANTS FOR DIENE POLYMERS WITH HIGH MOLECULAR WEIGHTS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1998-03-10 US claimed
EP-0700963-A1 Polymeric N-aryl substituted and N-alkaryl substituted diphenyldiamines THE GOODYEAR TIRE & RUBBER COMPANY (US) 1996-03-13 EP claimed
EP-0446555-B1 Polymeric diphenyldiamines GOODYEAR TIRE & RUBBER (US) 1994-09-21 EP claimed
EP-0446555-A1 Polymeric diphenyldiamines THE GOODYEAR TIRE & RUBBER COMPANY (US) 1991-09-18 EP claimed
US-5049625-A Ozone resistant rubber THE GOODYEAR TIRE & RUBBER COMPANY (US) 1991-09-17 US claimed
EP-0700963-B1 Polymeric N-aryl substituted and N-alkaryl substituted diphenyldiamines GOODYEAR TIRE & RUBBER (US) 1999-04-14 EP disclosed
US-5726248-A ANTIOXIDANTS FOR DIENE POLYMERS WITH HIGH MOLECULAR WEIGHTS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1998-03-10 US disclosed
EP-0700963-A1 Polymeric N-aryl substituted and N-alkaryl substituted diphenyldiamines THE GOODYEAR TIRE & RUBBER COMPANY (US) 1996-03-13 EP disclosed
EP-0446555-B1 Polymeric diphenyldiamines GOODYEAR TIRE & RUBBER (US) 1994-09-21 EP disclosed
EP-0446555-A1 Polymeric diphenyldiamines THE GOODYEAR TIRE & RUBBER COMPANY (US) 1991-09-18 EP disclosed
US-5049625-A Ozone resistant rubber THE GOODYEAR TIRE & RUBBER COMPANY (US) 1991-09-17 US disclosed
EP-0122213-B1 PROCESS FOR MAKING POLYMERIC COMPOUNDS PREPARED FROM DIPHENYLAMINE AND DIALKYLALKENYLBENZENE OR DIHYDROXYALKYLBENZENE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1989-03-22 EP disclosed
US-4537952-A Polymeric compounds prepared from diphenylamine and dialkylalkenylbenzene or dihydroxyalkylbenzene THE GOODYEAR TIRE & RUBBER COMPANY (US) 1985-08-27 US disclosed
EP-0122865-A1 Polymers with polymeric antioxidants prepared from diphenylamine and dialkylalkenylbenzene or dihydroxyalkylbenzene THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-10-24 EP disclosed
EP-0122213-A1 Process for making polymeric compounds prepared from diphenylamine and dialkylalkenylbenzene or dihydroxyalkylbenzene THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-10-17 EP disclosed
EP-0117831-A1 Stabilized polyester compositions THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-09-05 EP disclosed
US-4463170-A OXIDATION RESISTANCE STABILIZERS FOR POLYAMINES, POLYPHENYL RESINS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-07-31 US disclosed
US-4417017-A Polymeric antioxidants prepared from diphenyalmine and dialkylalkenylbenzene or dihydroxyalkylbenzene THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-11-22 US disclosed
US-4414348-A POLYMERIC DIPHENYLAMINE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-11-08 US disclosed