Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.46 |
| ▸ | CCR3 | P51677 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.41 |
| ▸ | ECE2 | P0DPD6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CALCRL | Q16602 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.39 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31286039 | 0.81 | OPRM1 (0.47) | OPRM1OPRD1OPRK1OGFRL1CCR3 | |
| SCHEMBL22605500 | 0.80 | OPRM1 (0.51) | OPRM1OPRD1OPRK1OGFRL1ALDH1A1 | |
| SCHEMBL22605593 | 0.78 | OPRM1 (0.51) | OPRM1OPRD1OPRK1OGFRL1HDAC1 | |
| SCHEMBL22605542 | 0.78 | OPRM1 (0.51) | OPRM1OPRD1OPRK1OGFRL1ALDH1A1 | |
| SCHEMBL29619947 | 0.78 | CCR3 (0.50) | CCR3HDAC3ECE2HDAC1HDAC2 | |
| SCHEMBL30317255 | 0.77 | CCR3 (0.44) | CCR3HDAC3ECE2HDAC1HDAC2 | |
| SCHEMBL22605698 | 0.75 | PLD2 (0.62) | OPRK1CALCRL | |
| SCHEMBL29518452 | 0.75 | PLD2 (0.62) | OPRK1CALCRL | |
| SCHEMBL31285861 | 0.73 | OPRM1 (0.65) | OPRM1OPRD1OPRK1OGFRL1ALDH1A1 | |
| SCHEMBL22588011 | 0.73 | OPRM1 (0.65) | OPRM1OPRD1OPRK1OGFRL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848598-B | Heterocyclic compound, application thereof and composition containing same | 健艾仕生物医药有限公司 | 2024-12-10 | — | — | CN | disclosed |
| CN-111848598-A | Heterocyclic ring-containing compound, application thereof and composition containing heterocyclic ring-containing compound | 健艾仕生物医药有限公司 | 2020-10-30 | — | — | CN | disclosed |
| WO-2020216378-A1 | HETEROCYCLIC COMPOUND, APPLICATION THEREOF, AND COMPOSITION CONTAINING SAME | 健艾仕生物医药有限公司 | 2020-10-29 | — | — | WO | disclosed |