Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 14/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ECE2 | P0DPD6 | 1/20 | 0.41 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24368197 | 0.80 | CALCRL (0.53) | CCR3 | |
| SCHEMBL29518303 | 0.80 | CALCRL (0.53) | CCR3 | |
| SCHEMBL22605756 | 0.78 | CCR3 (0.48) | CCR3 | |
| SCHEMBL22605648 | 0.78 | OPRM1 (0.46) | CCR3ECE2HDAC3HDAC1HDAC2 | |
| SCHEMBL30317255 | 0.77 | CCR3 (0.44) | CCR3ECE2HDAC3HDAC1HDAC2 | |
| SCHEMBL31286039 | 0.75 | OPRM1 (0.47) | CCR3ECE2HDAC3HDAC1HDAC2 | |
| SCHEMBL22588141 | 0.73 | PLD2 (0.51) | CCR3 | |
| SCHEMBL22605633 | 0.73 | TNKS (0.56) | CCR3 | |
| SCHEMBL31285839 | 0.73 | PLD2 (0.51) | CCR3 | |
| SCHEMBL22605698 | 0.72 | PLD2 (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022083731-A1 | FUSED RING-CONTAINING COMPOUND, APPLICATION THEREOF, AND COMPOSITION CONTAINING SAME | 健艾仕生物医药有限公司 | 2022-04-28 | — | — | WO | disclosed |