Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | ME2 | P23368 | 1/20 | 0.47 |
| ▸ | ME1 | P48163 | 1/20 | 0.47 |
| ▸ | ME3 | Q16798 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.45 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 3/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 3/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22605739 | 0.88 | CTSS (0.55) | HSD11B1HRH3ME2ME1ME3 | |
| SCHEMBL22587922 | 0.86 | CACNA1G (0.51) | HSD11B1HRH3ME2ME1ME3 | |
| SCHEMBL22587798 | 0.83 | CACNA1G (0.44) | HSD11B1HRH3ME2ME1ME3 | |
| SCHEMBL22594434 | 0.81 | HSD11B1 (0.73) | HSD11B1CTSS | |
| SCHEMBL22587888 | 0.81 | TNKS (0.49) | HSD11B1HRH3ME2ME1ME3 | |
| SCHEMBL30317157 | 0.81 | HSD11B1 (0.73) | HSD11B1CTSS | |
| SCHEMBL22605684 | 0.81 | OPRL1 (0.47) | HSD11B1HRH3CACNA1GCACNA1HCTSS | |
| SCHEMBL22605543 | 0.80 | HSD11B1 (0.59) | HSD11B1HRH3CTSSOPRD1 | |
| SCHEMBL22588034 | 0.78 | HSD11B1 (0.57) | HSD11B1HRH3ME2ME1ME3 | |
| SCHEMBL22605809 | 0.78 | IDO1 (0.47) | HSD11B1HRH3ME2ME1ME3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848598-A | Heterocyclic ring-containing compound, application thereof and composition containing heterocyclic ring-containing compound | 健艾仕生物医药有限公司 | 2020-10-30 | — | — | CN | disclosed |
| WO-2020216378-A1 | HETEROCYCLIC COMPOUND, APPLICATION THEREOF, AND COMPOSITION CONTAINING SAME | 健艾仕生物医药有限公司 | 2020-10-29 | — | — | WO | disclosed |