Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.64 |
| ▸ | HPGD | P15428 | 6/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22607228 | 0.86 | MAPT (0.61) | MAPTHPGDTSHRALDH1A1POLB | |
| SCHEMBL21592193 | 0.76 | CA12 (0.69) | MAPTHPGDTSHRALDH1A1POLB | |
| SCHEMBL279942 | 0.75 | HSD17B10 (0.49) | MAPTHPGDTSHRALDH1A1POLB | |
| SCHEMBL28214077 | 0.74 | RAB9A (0.54) | MAPTHPGDALDH1A1POLBKMT2A | |
| SCHEMBL11522174 | 0.74 | PKM (0.59) | POLBNPC1RAB9AHSD17B10LMNA | |
| SCHEMBL31522206 | 0.73 | MAPT (0.67) | MAPTHPGDTSHRALDH1A1POLB | |
| SCHEMBL31522207 | 0.73 | MAPT (0.67) | MAPTHPGDTSHRALDH1A1POLB | |
| SCHEMBL31522233 | 0.73 | MAPT (0.88) | MAPTHPGDTSHRALDH1A1POLB | |
| SCHEMBL16157172 | 0.72 | MAPT (0.80) | MAPTHPGDTSHRALDH1A1POLB | |
| SCHEMBL31522210 | 0.72 | MAPT (0.88) | MAPTHPGDTSHRALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11654138-B2 | Therapeutic agents for treating and preventing autoimmune diseases and cancer and a screening method | King Faisal University (SA) | 2023-05-23 | — | — | US | disclosed |
| US-11654138-B2 | Therapeutic agents for treating and preventing autoimmune diseases and cancer and a screening method | King Faisal University (SA) | 2023-05-23 | — | — | US | disclosed |
| WO-2022003439-A1 | THERAPEUTIC AGENTS FOR TREATING AND PREVENTING AUTOIMMUNE DISEASES AND CANCER AND A SCREENING METHOD | King Faisal University (SA) | 2022-01-06 | — | — | WO | disclosed |
| US-20210186944-A1 | THERAPEUTIC AGENTS FOR TREATING AND PREVENTING AUTOIMMUNE DISEASES AND CANCER AND A SCREENING METHOD | King Faisal University (SA) | 2021-06-24 | — | — | US | disclosed |
| US-20200338058-A1 | THERAPEUTIC AGENTS FOR TREATING AND PREVENTING AUTOIMMUNE DISEASES AND CANCER AND A SCREENING METHOD | King Faisal University (SA) | 2020-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210186944-A1 | THERAPEUTIC AGENTS FOR TREATING AND PREVENTING AUTOIMMUNE DISEASES AND CANCER AND A SCREENING METHOD | ARID2, API5, UACA | MAPT 4537/4885HPGD 3393/4885TSHR 2358/4885 |
| US-11654138-B2 | Therapeutic agents for treating and preventing autoimmune diseases and cancer and a screening method | ARID2, API5, UACA | MAPT 4537/4885HPGD 3393/4885TSHR 2358/4885 |
| US-20200338058-A1 | THERAPEUTIC AGENTS FOR TREATING AND PREVENTING AUTOIMMUNE DISEASES AND CANCER AND A SCREENING METHOD | ARID2, API5, UACA | MAPT 4537/4885HPGD 3393/4885TSHR 2358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.