Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | CCR8 | P51685 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6645913 | 0.79 | MAPT (0.53) | RAB9AMAPTKDM4EALDH1A1GAA | |
| SCHEMBL81827 | 0.78 | HCAR3 (0.55) | RAB9AMAPTKDM4EALDH1A1GAA | |
| SCHEMBL24616543 | 0.77 | NPC1 (0.43) | RAB9AMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL20613270 | 0.76 | RAB9A (0.50) | RAB9AMAPTKDM4EALDH1A1GAA | |
| SCHEMBL23182690 | 0.76 | RAB9A (0.50) | RAB9AMAPTKDM4EALDH1A1GAA | |
| SCHEMBL14985165 | 0.76 | RAB9A (0.55) | RAB9AMAPTKDM4EALDH1A1GAA | |
| SCHEMBL4979793 | 0.75 | RAB9A (0.52) | RAB9AMAPTALDH1A1GAAKMT2A | |
| SCHEMBL10293613 | 0.74 | HCAR3 (0.57) | RAB9AMAPTKDM4EALDH1A1GAA | |
| SCHEMBL12327200 | 0.73 | HCAR3 (0.58) | RAB9AMAPTKDM4EALDH1A1GAA | |
| SCHEMBL13103613 | 0.73 | RAB9A (0.47) | RAB9AMAPTKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020216350-A1 | QUINOLINE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | 中国人民解放军军事科学院军事医学研究院 | 2020-10-29 | — | — | WO | disclosed |