Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.40 |
| ▸ | MMP12 | P39900 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 6/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22607824 | 1.00 | FFAR1 (0.40) | FFAR1MMP12MMP2MMP9PTGES | |
| SCHEMBL22624596 | 0.86 | PTGES (0.39) | FFAR1PTGESGRM5 | |
| SCHEMBL29943707 | 0.86 | PTGES (0.39) | FFAR1PTGESGRM5 | |
| SCHEMBL22607864 | 0.76 | FFAR1 (0.38) | FFAR1PTGES | |
| SCHEMBL22607867 | 0.76 | FFAR1 (0.38) | FFAR1PTGES | |
| SCHEMBL27581966 | 0.75 | MME (0.44) | MMP12MMP2MMP9MMP13TRPA1 | |
| SCHEMBL16150972 | 0.70 | NPC1 (0.50) | FFAR1PTGESGRM5CYP2A6 | |
| SCHEMBL22607933 | 0.69 | FOLH1 (0.45) | FFAR1PTGESFOLH1TRPA1 | |
| SCHEMBL22607932 | 0.69 | FOLH1 (0.45) | FFAR1PTGESFOLH1TRPA1 | |
| SCHEMBL28027446 | 0.69 | PNMT (0.50) | FFAR1FOLH1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11667630-B2 | Nitrogen-containing 6-membered cyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2023-06-06 | — | — | US | disclosed |
| US-20210188837-A1 | NITROGEN-CONTAINING 6-MEMBERED CYCLIC COMPOUND | ASAHI KASEI PHARMA CORPORATION (JP) | 2021-06-24 | — | — | US | disclosed |
| US-10988468-B2 | Nitrogen-containing 6-membered cyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2021-04-27 | — | — | US | disclosed |
| US-20200347046-A1 | NITROGEN-CONTAINING 6-MEMBERED CYCLIC COMPOUND | ASAHI KASEI PHARMA CORPORATION (JP) | 2020-11-05 | — | — | US | disclosed |
| EP-3733665-A1 | NITROGEN-CONTAINING SIX-MEMBERED RING COMPOUND | Asahi Kasei Pharma Corporation (JP) | 2020-11-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188837-A1 | NITROGEN-CONTAINING 6-MEMBERED CYCLIC COMPOUND | PTGER4, EPB41, BMP4 | FFAR1 183/4885MMP12 444/4885MMP2 556/4885 |
| US-10988468-B2 | Nitrogen-containing 6-membered cyclic compound | PTGER4, EPB41, BMP4 | FFAR1 183/4885MMP12 444/4885MMP2 556/4885 |
| US-11667630-B2 | Nitrogen-containing 6-membered cyclic compound | PTGER4, EPB41, BMP4 | FFAR1 183/4885MMP12 444/4885MMP2 556/4885 |
| US-20200347046-A1 | NITROGEN-CONTAINING 6-MEMBERED CYCLIC COMPOUND | PTGER4, EPB41, BMP4 | FFAR1 183/4885MMP12 444/4885MMP2 556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.