⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27483243 | 0.80 | — | — | |
| SCHEMBL10521078 | 0.75 | MAPT (0.64) | — | |
| SCHEMBL10521083 | 0.75 | MAPT (0.64) | — | |
| SCHEMBL8866037 | 0.74 | TRPA1 (0.48) | — | |
| Trimethylammonium SCHEMBL28780678 | 0.74 | MAPT (0.49) | — | |
| SCHEMBL7772673 | 0.74 | PTPN1 (0.47) | — | |
| SCHEMBL10070535 | 0.74 | MAPT (0.38) | — | |
| SCHEMBL4256312 | 0.73 | ALDH5A1 (0.80) | — | |
| Formaldehyde SCHEMBL27533174 | 0.73 | MAPT (0.47) | — | |
| SCHEMBL10806096 | 0.72 | MAPT (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108117534-B | Benzo-oxygenated aliphatic cyclomethylamines | 华东理工大学 | 2021-02-05 | — | — | CN | disclosed |
| US-8697881-B2 | Method for producing alcohol compound | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2014-04-15 | — | — | US | disclosed |
| EP-2374783-A1 | METHOD FOR PRODUCING ALCOHOL COMPOUND | Takasago International Corporation (JP) | 2011-10-12 | — | — | EP | disclosed |
| US-20110201820-A1 | METHOD FOR PRODUCING ALCOHOL COMPOUND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-08-18 | — | — | US | disclosed |
| EP-1263735-B1 | ACID ADDITION SALTS OF IMIDAZOLIDINONES AS REACTION CATALYSTS | UNIV CALIFORNIA (US) | 2007-07-04 | — | — | EP | disclosed |
| US-6887871-B2 | Use of phenylheteroakylamine derivatives | ASTRAZENECA AB (SE) | 2005-05-03 | — | — | US | disclosed |
| EP-1263711-B1 | NOVEL USE OF PHENYLHETEROALKYLAMINE DERIVATIVES | ASTRAZENECA AB (SE) | 2004-12-15 | — | — | EP | disclosed |
| US-6667406-B1 | Using facile intramolecular Diels Alder reaction | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2003-12-23 | — | — | US | disclosed |
| US-20030158185-A1 | Novel use of phenylheteroakylamine derivatives | ASTRAZENECA AB (SE) | 2003-08-21 | — | — | US | disclosed |
| US-6534434-B2 | Catalyst for unsaturated carbonyl compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-03-18 | — | — | US | disclosed |
| US-20020013475-A1 | Chiral imidazolidinone-based catalyst composition and reaction system | MACMILLAN DAVID W C (US) | 2002-01-31 | — | — | US | disclosed |
| WO-2001062704-A1 | NOVEL USE OF PHENYLHETEROALKYLAMINE DERIVATIVES | ASTRAZENECA AB (SE) | 2001-08-30 | — | — | WO | disclosed |
| WO-2001053241-A1 | CHEMICAL TRANSFORMATION OF SUBSTRATES USING NONMETALLIC, ORGANIC CATALYST COMPOSITIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2001-07-26 | — | — | WO | disclosed |
| WO-2001053269-A1 | ACID ADDITION SALTS OF IMIDAZOLIDINONES AS REACTION CATALYSTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2001-07-26 | — | — | WO | disclosed |
| EP-0460883-B1 | Process for beta-hydroxy-alpha-amino acids | UNIV NOTRE DAME DU LAC (US) | 1997-01-15 | — | — | EP | disclosed |
| US-5294737-A | Hydrolysis, cyclization, condensation | THE RESEARCH FOUNDATION STATE UNIVERSITY OF NEW YORK (US) | 1994-03-15 | — | — | US | disclosed |
| US-5266468-A | Process for preparing β-hydroxy-α amino acids | UNIVERSITY OF NOTRE DAME DU LAC (US) | 1993-11-30 | — | — | US | disclosed |
| CN-1058046-A | The method for preparing beta-hydroxy-a-amino acid | UNIV NOTRE DAME DU LAC (US) | 1992-01-22 | — | — | CN | disclosed |
| EP-0460883-A2 | Process for beta-hydroxy-alpha-amino acids | THE UNIVERSITY OF NOTRE DAME DU LAC (US) | 1991-12-11 | — | — | EP | disclosed |
| EP-0320628-A1 | Substituted furan compounds which are useful in inhibiting lipoxygenase enzymes, particularly 5-lipoxygenase | ABBOTT LABORATORIES (US) | 1989-06-21 | — | — | EP | disclosed |