Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 3/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | EPOR | P19235 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22608475 | 1.00 | TP53 (0.49) | TP53MAPTALDH1A1L3MBTL1LMNA | |
| SCHEMBL22608472 | 1.00 | TP53 (0.49) | TP53MAPTALDH1A1L3MBTL1LMNA | |
| SCHEMBL28406626 | 0.94 | TP53 (0.47) | TP53MAPTALDH1A1L3MBTL1LMNA | |
| SCHEMBL28400999 | 0.94 | TP53 (0.47) | TP53MAPTALDH1A1L3MBTL1LMNA | |
| SCHEMBL28401001 | 0.94 | TP53 (0.47) | TP53MAPTALDH1A1L3MBTL1LMNA | |
| SCHEMBL19617430 | 0.86 | TP53 (0.50) | TP53MAPTALDH1A1L3MBTL1LMNA | |
| SCHEMBL22608280 | 0.86 | ALDH1A1 (0.45) | TP53MAPTALDH1A1L3MBTL1LMNA | |
| SCHEMBL22608278 | 0.86 | ALDH1A1 (0.45) | TP53MAPTALDH1A1L3MBTL1LMNA | |
| SCHEMBL22608277 | 0.86 | ALDH1A1 (0.45) | TP53MAPTALDH1A1L3MBTL1LMNA | |
| SCHEMBL7950550 | 0.81 | CA1 (0.41) | TP53ALDH1A1L3MBTL1LMNAALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3733648-B1 | METHOD FOR PREPARING 5R-BENZYLOXYAMINOPIPERIDIN-2S-CARBOXYLIC ACID OR DERIVATIVE THEREOF | XINFA PHARMACEUTICAL CO LTD (CN) | 2022-06-08 | — | — | EP | disclosed |
| US-20210323920-A1 | METHOD OF PREPARING 5R-[(BENZYLOXY) AMINO] PIPERIDINE-2S-CARBOXYLIC ACID OR A DERIVATIVE THEREOF | XINFA PHARMACEUTICAL CO., LTD (CN) | 2021-10-21 | — | — | US | disclosed |
| US-11142499-B1 | Method of preparing 5R-[(benzyloxy) amino] piperidine-2S-carboxylic acid or a derivative thereof | XINFA PHARMACEUTICAL CO., LTD (CN) | 2021-10-12 | — | — | US | disclosed |
| CN-109970625-B | Preparation method of 5R-benzyloxyaminopiperidine-2S-formic acid or derivative thereof | 新发药业有限公司 | 2021-02-26 | — | — | CN | disclosed |
| EP-3733648-A1 | METHOD FOR PREPARING 5R-BENZYLOXYAMINOPIPERIDIN-2S-CARBOXYLIC ACID OR DERIVATIVE THEREOF | Xinfa Pharmaceutical Co., Ltd (CN) | 2020-11-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11142499-B1 | Method of preparing 5R-[(benzyloxy) amino] piperidine-2S-carboxylic acid or a derivative thereof | GLUL, GRIN2D, GRIN2C | TP53 3931/4885MAPT 3757/4885ALDH1A1 221/4885 |
| US-20210323920-A1 | METHOD OF PREPARING 5R-[(BENZYLOXY) AMINO] PIPERIDINE-2S-CARBOXYLIC ACID OR A DERIVATIVE THEREOF | GLUL, GRIN2D, GRIN2C | TP53 3931/4885MAPT 3757/4885ALDH1A1 221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.