Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | CCKBR | P32239 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8207184 | 0.83 | SYK (0.40) | CA1CA2CA4SMN1; SMN2LMNA | |
| SCHEMBL22608472 | 0.81 | TP53 (0.49) | ALOX5SMN1; SMN2LMNAALDH1A1KMT2A | |
| SCHEMBL22608474 | 0.81 | TP53 (0.49) | ALOX5SMN1; SMN2LMNAALDH1A1KMT2A | |
| SCHEMBL22608475 | 0.81 | TP53 (0.49) | ALOX5SMN1; SMN2LMNAALDH1A1KMT2A | |
| SCHEMBL7948027 | 0.81 | TDP1 (0.40) | CA1CA2ALOX5CA4SMN1; SMN2 | |
| SCHEMBL11898463 | 0.78 | ALOX5 (0.40) | ALOX5LTA4H | |
| SCHEMBL339168 | 0.78 | ALDH1A1 (0.61) | CA1CA2CA4LMNAALDH1A1 | |
| SCHEMBL7948959 | 0.78 | ALOX5 (0.46) | CA1CA2ALOX5CA4LMNA | |
| SCHEMBL22608278 | 0.77 | ALDH1A1 (0.45) | LMNAALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL22608280 | 0.77 | ALDH1A1 (0.45) | LMNAALDH1A1MEN1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6254850-B1 | POLYCARBOXYALKYLAMINOALKANES FOR COMPLEXES | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-07-03 | — | — | US | disclosed |
| US-6040432-A | Metal complexes, of DTPA derivatives suitable for use in diagnosis and therapy | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-03-21 | — | — | US | disclosed |