Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6671103 | 0.80 | MAPT (0.47) | MAPTMEN1KMT2ALMNARAB9A | |
| SCHEMBL449938 | 0.73 | ELANE (0.59) | MAPTMEN1KMT2ALMNARAB9A | |
| SCHEMBL154474 | 0.72 | LMNA (0.64) | MAPTMEN1KMT2ALMNARAB9A | |
| SCHEMBL11579928 | 0.70 | LMNA (0.61) | MAPTMEN1KMT2ALMNARAB9A | |
| SCHEMBL28599109 | 0.70 | LMNA (0.61) | MAPTMEN1KMT2ALMNARAB9A | |
| SCHEMBL10140684 | 0.70 | KMT2A (0.41) | MEN1KMT2ANPC1POLB | |
| SCHEMBL14125424 | 0.68 | LDHA (0.40) | MAPTMEN1KMT2ALMNARAB9A | |
| SCHEMBL1290072 | 0.68 | MGLL (0.47) | MAPTMEN1KMT2ALMNARAB9A | |
| SCHEMBL11721534 | 0.68 | TDP1 (0.40) | MAPTRAB9AELANEALDH1A1NPC1 | |
| SCHEMBL10237396 | 0.67 | LMNA (0.57) | MAPTMEN1KMT2ALMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3731840-A1 | GLYCOLATE OXIDASE INHIBITORS AND USE THEREOF | Orfan Biotech Inc. (US) | 2020-11-04 | — | — | EP | disclosed |