Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPOR | P19235 | 5/20 | 0.39 |
| ▸ | APP | P05067 | 4/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22609452 | 0.93 | EPOR (0.41) | EPORAPPACHEALDH1A1NPSR1 | |
| SCHEMBL21069213 | 0.86 | IDO1 (0.43) | NPSR1 | |
| SCHEMBL21070460 | 0.80 | MAOA (0.37) | — | |
| SCHEMBL21070300 | 0.80 | IDO1 (0.43) | ACHENPSR1 | |
| SCHEMBL21070199 | 0.80 | LTA4H (0.39) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL21070657 | 0.77 | ALDH1A1 (0.40) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL21070298 | 0.77 | ALDH1A1 (0.40) | ALDH1A1NPSR1TSHR | |
| SCHEMBL21069389 | 0.77 | ALDH1A1 (0.36) | EPORALDH1A1 | |
| SCHEMBL21070134 | 0.77 | ALDH1A1 (0.36) | EPORALDH1A1 | |
| SCHEMBL25957834 | 0.75 | ALDH1A1 (0.41) | ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3731869-A1 | IRAK DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2020-11-04 | — | — | EP | disclosed |