Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 1/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.46 |
| ▸ | WNT3A | P56704 | 9/20 | 0.45 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20508088 | 0.91 | WNT3A (0.46) | MAPK1TLR9TLR8TLR7WNT3A | |
| SCHEMBL20507984 | 0.91 | WNT3A (0.52) | TLR9TLR8TLR7WNT3A | |
| SCHEMBL20508222 | 0.88 | WNT3A (0.46) | TLR9TLR8TLR7WNT3A | |
| SCHEMBL20508074 | 0.88 | WNT3A (0.47) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL20507866 | 0.87 | TLR9 (0.43) | TLR9TLR8TLR7WNT3APORCN | |
| SCHEMBL20507955 | 0.86 | WNT3A (0.46) | TLR9TLR8TLR7WNT3A | |
| SCHEMBL20508011 | 0.86 | MAPK1 (0.46) | MAPK1TLR9TLR8TLR7WNT3A | |
| SCHEMBL20508067 | 0.85 | WNT3A (0.45) | TLR9TLR8TLR7WNT3APORCN | |
| SCHEMBL20507980 | 0.85 | WNT3A (0.55) | WNT3APORCN | |
| SCHEMBL20507968 | 0.85 | WNT3A (0.54) | WNT3APORCN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10821104-B2 | Five-membered heterocyclic amides WNT pathway inhibitor | Suzhou Sinovent Pharmaceuticals Co., Ltd. (CN) | 2020-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10821104-B2 | Five-membered heterocyclic amides WNT pathway inhibitor | WNT1, WNT3, WNT3A | PSEN1 4291/4885PSEN2 4248/4885APH1B 538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.