Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1979744 | 0.89 | ALDH1A1 (0.48) | ALOX15ALDH1A1PKMKDM4EMEN1 | |
| SCHEMBL14403192 | 0.78 | ALOX15 (0.46) | ALOX15ALDH1A1PKMKDM4EMEN1 | |
| SCHEMBL14403317 | 0.78 | ALOX15 (0.46) | ALOX15ALDH1A1PKMKDM4EMEN1 | |
| SCHEMBL28803958 | 0.78 | ALDH1A1 (0.39) | ALOX15ALDH1A1PKMKDM4EMEN1 | |
| SCHEMBL11204020 | 0.77 | CYP4F2 (0.42) | ALOX15ALDH1A1PKMKDM4EMEN1 | |
| SCHEMBL125138 | 0.77 | ALDH1A1 (0.46) | ALOX15ALDH1A1PKMKDM4EMEN1 | |
| Water SCHEMBL4000009 | 0.77 | MEN1 (0.44) | ALOX15ALDH1A1PKMKDM4EMEN1 | |
| SCHEMBL3372776 | 0.77 | ALDH1A1 (0.42) | ALOX15ALDH1A1PKMKDM4EMEN1 | |
| SCHEMBL29083077 | 0.77 | ALDH1A1 (0.42) | ALOX15ALDH1A1PKMKDM4EMEN1 | |
| SCHEMBL29756467 | 0.77 | ALDH1A1 (0.37) | ALOX15ALDH1A1PKMKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10828305-B2 | Nitrogenous heterocyclic compound, preparation method, intermediate, composition and use | SHANGHAI PHARMACEUTICALS HOLDING CO., LTD. (CN) | 2020-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10828305-B2 | Nitrogenous heterocyclic compound, preparation method, intermediate, composition and use | ERBB2, EGFR, ERBB4 | ALOX15 2841/4885ALDH1A1 3908/4885PKM 3224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.