⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1245673 | 0.67 | — | — | |
| SCHEMBL441985 | 0.53 | — | — | |
| SCHEMBL8869174 | 0.51 | — | — | |
| SCHEMBL21621581 | 0.50 | GSK3A (0.35) | — | |
| SCHEMBL16870058 | 0.48 | CASP3 (0.48) | — | |
| SCHEMBL13559905 | 0.47 | — | — | |
| Ethane SCHEMBL18258578 | 0.47 | — | — | |
| Ethane SCHEMBL11390749 | 0.47 | GSK3A (0.85) | — | |
| SCHEMBL25436194 | 0.47 | MGLL (1.00) | — | |
| Methyl Alcohol SCHEMBL11805222 | 0.46 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200347045-A1 | CRBN LIGANDS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2020-11-05 | — | — | US | disclosed |