Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26152318 | 0.78 | HSD11B1 (0.36) | HSD11B1 | |
| SCHEMBL22624043 | 0.73 | KDM4E (0.35) | KDM4E | |
| SCHEMBL21347098 | 0.71 | HSD11B1 (0.32) | HSD11B1 | |
| SCHEMBL25543614 | 0.71 | HSD11B1 (0.32) | HSD11B1 | |
| SCHEMBL20727450 | 0.69 | HSD11B1 (0.35) | HSD11B1 | |
| SCHEMBL22887047 | 0.69 | HSD11B1 (0.35) | HSD11B1 | |
| SCHEMBL21948554 | 0.69 | HSD11B1 (0.35) | HSD11B1 | |
| SCHEMBL18819429 | 0.69 | — | — | |
| SCHEMBL17987328 | 0.68 | KDM4E (0.36) | KDM4E | |
| SCHEMBL22105484 | 0.68 | FYN (0.31) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200347071-A1 | AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2020-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200347071-A1 | AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS | RIPK1, RIPK2, RIPK4 | KDM4E 1830/4885HSD11B1 4143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.