Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 7/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22625123 | 0.88 | STS (0.34) | MAOBMAOA | |
| SCHEMBL22625362 | 0.86 | NPC1 (0.46) | RAB9ANPC1ALDH1A1HPGDKDM4E | |
| SCHEMBL22625152 | 0.85 | RAB9A (0.35) | RAB9ANPC1MAOBMAOAALDH1A1 | |
| SCHEMBL22625236 | 0.85 | RAB9A (0.36) | RAB9ANPC1MAOBMAOAALDH1A1 | |
| SCHEMBL25849401 | 0.83 | MAOB (0.40) | RAB9ANPC1MAOBMAOAALDH1A1 | |
| SCHEMBL22625405 | 0.83 | RAB9A (0.39) | RAB9ANPC1MAOBMAOAALDH1A1 | |
| SCHEMBL22625364 | 0.82 | MAOA (0.32) | MAOBMAOA | |
| SCHEMBL22625233 | 0.80 | RAB9A (0.38) | RAB9ANPC1MAOBMAOAALDH1A1 | |
| SCHEMBL22625245 | 0.80 | MAOB (0.33) | RAB9ANPC1MAOBMAOAALDH1A1 | |
| SCHEMBL22625385 | 0.79 | NPC1 (0.39) | RAB9ANPC1MAOBMAOAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3583102-B1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |