Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.33 |
| ▸ | MAOA | P21397 | 3/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.32 |
| ▸ | HPGD | P15428 | 4/20 | 0.32 |
| ▸ | GLA | P06280 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25855079 | 0.88 | KDM4E (0.36) | MAOBMAOAS1PR1PTPN7S1PR3 | |
| SCHEMBL22625234 | 0.88 | NPC1 (0.38) | MAOBMAOAS1PR1KDM4EHPGD | |
| SCHEMBL22625093 | 0.87 | S1PR1 (0.33) | MAOBMAOAS1PR1PTPN7S1PR3 | |
| SCHEMBL22625307 | 0.86 | THRB (0.39) | MAOBMAOAS1PR1PTPN7S1PR3 | |
| SCHEMBL22624927 | 0.86 | NPC1 (0.34) | MAOBMAOAS1PR1PTPN7S1PR3 | |
| SCHEMBL22625077 | 0.84 | MAOB (0.34) | MAOBMAOAS1PR1PTPN7S1PR3 | |
| SCHEMBL22625364 | 0.83 | MAOA (0.32) | MAOBMAOAS1PR1S1PR3SLC10A1 | |
| SCHEMBL22625129 | 0.83 | STS (0.33) | MAOBMAOAS1PR1PTPN7S1PR3 | |
| SCHEMBL22625358 | 0.81 | NPC1 (0.48) | S1PR1KDM4EHPGDGLANPC1 | |
| SCHEMBL22625233 | 0.81 | RAB9A (0.38) | MAOBMAOAKDM4EHPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3583102-B1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |