Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17868237 | 0.82 | P2RX7 (0.33) | KDRPARP1 | |
| SCHEMBL22727513 | 0.76 | USP30 (0.31) | — | |
| SCHEMBL22718273 | 0.74 | PARP1 (0.34) | PARP1 | |
| SCHEMBL28699292 | 0.74 | PARP1 (0.34) | PARP1 | |
| SCHEMBL22719152 | 0.71 | PARP1 (0.34) | PARP1 | |
| SCHEMBL29829859 | 0.71 | GAA (0.35) | PARP1 | |
| SCHEMBL22746961 | 0.70 | HSD17B10 (0.38) | PARP1 | |
| SCHEMBL17868262 | 0.70 | ALDH1A1 (0.32) | KDRPARP1 | |
| SCHEMBL31569029 | 0.69 | MAPK1 (0.36) | — | |
| SCHEMBL24775047 | 0.69 | PARP1 (0.33) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020221824-A1 | NOVEL INDOLIZINE-2-CARBOXAMIDES ACTIVE AGAINST THE HEPATITIS B VIRUS (HBV) | AICURIS GMBH & CO. KG (DE) | 2020-11-05 | — | — | WO | disclosed |